TY - JOUR
T1 - Subcellular distribution, and physical and immunological properties of hepathic alanine
T2 - Glyoxylate aminotransferase isoenzymes in different mammalian species
AU - Takada, Yoshikazu
AU - Noguchi, Tomoo
PY - 1982
Y1 - 1982
N2 - 1. 1. Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes 1 and 2 were examined with ten different mammalian species. 2. 2. Intracellular organelles containing isoenzyme 1 varied from species to species; isoenzyme 1 was located in the peroxisomes, mitochondria or both organelles. In contrast, isoenzyme 2 was found only in the mitochondria but not in the peroxisomes. 3. 3. In any species, isoenzyme 1 had molecular weight of approx. 80,000 with two identical subunits, and isoenzyme 2 approx. 200,000 with four identical subunits. 4. 4. In any species, an immunological cross-reactivity was observed among isoenzymes 1 and among isoenzymes 2 but did not between isoenzymes 1 and isoenzymes 2.
AB - 1. 1. Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes 1 and 2 were examined with ten different mammalian species. 2. 2. Intracellular organelles containing isoenzyme 1 varied from species to species; isoenzyme 1 was located in the peroxisomes, mitochondria or both organelles. In contrast, isoenzyme 2 was found only in the mitochondria but not in the peroxisomes. 3. 3. In any species, isoenzyme 1 had molecular weight of approx. 80,000 with two identical subunits, and isoenzyme 2 approx. 200,000 with four identical subunits. 4. 4. In any species, an immunological cross-reactivity was observed among isoenzymes 1 and among isoenzymes 2 but did not between isoenzymes 1 and isoenzymes 2.
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U2 - 10.1016/0305-0491(82)90512-0
DO - 10.1016/0305-0491(82)90512-0
M3 - Article
C2 - 7128113
AN - SCOPUS:0020007130
VL - 72
SP - 597
EP - 604
JO - Comparative biochemistry and physiology. B, Comparative biochemistry
JF - Comparative biochemistry and physiology. B, Comparative biochemistry
SN - 0305-0491
IS - 4
ER -