Static and dynamic characteristics of cerebral blood flow during the resting state

Qihong Zou, Changwei W. Wu, Elliot A. Stein, Yufeng Zang, Yihong Yang

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155 引文 斯高帕斯(Scopus)

摘要

In this study, the static and dynamic characteristics of cerebral blood flow (CBF) in the resting state were investigated using an arterial spin labeling (ASL) perfusion imaging technique. Consistent with previous PET results, static CBF measured by ASL was significantly higher in the posterior cingulate cortex (PCC), thalamus, insula/superior temporal gyrus (STG) and medial prefrontal cortex (MPFC) than the average CBF of the brain. The dynamic measurement of CBF fluctuations showed high correlation (functional connectivity) between components in the default mode network. These brain regions also had high local temporal synchrony and high fluctuation amplitude, as measured by regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) analyses. The spatial pattern of the static CBF correlated well with that of the dynamic indices. The high static and dynamic activities in the PCC, MPFC, insula/STG and thalamus suggest that these regions play a vital role in maintaining and facilitating fundamental brain functions.
原文英語
頁(從 - 到)515-524
頁數10
期刊NeuroImage
48
發行號3
DOIs
出版狀態已發佈 - 11月 15 2009
對外發佈

ASJC Scopus subject areas

  • 神經內科
  • 認知神經科學

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