Spontaneous pneumothorax in flight as first manifestation of alpha-1 antitrypsin deficiency

Yi Chang Lin, Wen Kuan Chiu, Hung Chang, Yeung Leung Cheng, Jen Chin Chen

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

Alpha-1 antitrypsin deficiency is a genetic condition that increases the risk of a variety of conditions including pulmonary emphysema and chronic liver disease. We report on a 33-yr-old male fighter pilot with early-onset pulmonary emphysema with bullae who developed spontaneous pneumothorax during in-flight combat training. A CT scan of his chest after removal of the chest tube showed multiple variably sized bullae and pulmonary cysts scattered throughout both lungs. Serum levels of alpha-1 antitrypsin were markedly decreased. Genetic analyses showed a PI ZZ genotype. Alpha-1 antitrypsin deficiency often goes undiagnosed by flight surgeons, which is a risk to flight safety.
原文英語
頁(從 - 到)704-706
頁數3
期刊Aviation Space and Environmental Medicine
79
發行號7
DOIs
出版狀態已發佈 - 七月 2008
對外發佈Yes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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