摘要
A specific, acquired chromosomal abnormality (deletion 3p) has been found in at least one chromosome 3 in 100 percent of the metaphases in 12 of 12 cell lines cultured from human small-cell lung cancer tissue and in 2-day tumor culture specimens from three patients. Analysis of the shortest region of overlap shows the deletion to be 3p(14-23). This specific change was not seen in five of five lung cancer cell lines other than small-cell lung cancer or in two lymphoblastoid lines cultured from cells of small-cell lung cancer patients whose tumors had the 3p deletion.
原文 | 英語 |
---|---|
頁(從 - 到) | 181-182 |
頁數 | 2 |
期刊 | Science |
卷 | 215 |
發行號 | 4529 |
出版狀態 | 已發佈 - 1月 1 1982 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 醫藥 (全部)
- 多學科