摘要
A specific, acquired chromosomal abnormality (deletion 3p) has been found in at least one chromosome 3 in 100 percent of the metaphases in 12 of 12 cell lines cultured from human small-cell lung cancer tissue and in 2-day tumor culture specimens from three patients. Analysis of the shortest region of overlap shows the deletion to be 3p(14-23). This specific change was not seen in five of five lung cancer cell lines other than small-cell lung cancer or in two lymphoblastoid lines cultured from cells of small-cell lung cancer patients whose tumors had the 3p deletion.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 181-182 |
| 頁數 | 2 |
| 期刊 | Science |
| 卷 | 215 |
| 發行號 | 4529 |
| 出版狀態 | 已發佈 - 一月 1 1982 |
| 對外發佈 | Yes |
ASJC Scopus subject areas
- Medicine(all)
- General
指紋 深入研究「Specific chromosome defect associated with human small-cell lung cancer: Deletion 3p(14-23)」主題。共同形成了獨特的指紋。
引用此
Whang-Peng, J., Kao-Shan, C. S., Lee, E. C., Bunn, P. A., Carney, D. N., Gazdar, A. F., & Minna, J. D. (1982). Specific chromosome defect associated with human small-cell lung cancer: Deletion 3p(14-23). Science, 215(4529), 181-182.