Sparing Immunosuppression in Heart Transplant Recipients With Severe Sepsis

N. K. Chou, W. J. Ko, N. H. Chi, Y. S. Chen, H. Y. Yu, R. B. Hsu, C. T. Fang, S. C. Chang, F. Y. Lin, S. H. Chu, S. S. Wang

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

摘要

This study described an analysis of severe sepsis among heart transplantation recipients who were treated by sparing all immunosuppressants. Sepsis leading to multiple organ failure (MOF) in heart transplantation has a high mortality. This retrospective study of 190 patients who underwent heart transplantation from 1993 to 2004 included 12 who had severe sepsis with MOF who were treated by sparing all immunosuppressants. Half of them survived after sparing all immunosuppressants with intensive endomyocardial biopsy. Only one case needed pulse therapy for an acute rejection episode. The most common bacterial infectious episodes were caused by methicillin-resistant Staphylococcus aureus (n = 3). All sepsis episodes occurred in the first month after heart transplantation except in one case, which occurred 6 years after heart transplantation. There was a 50% survival rate of heart transplantation recipients who experienced MOF due to severe sepsis and were treated by sparing all immunosuppressants under a program of intensive endomyocardial biopsy.

原文英語
頁(從 - 到)2145-2146
頁數2
期刊Transplantation Proceedings
38
發行號7
DOIs
出版狀態已發佈 - 九月 2006
對外發佈Yes

    指紋

ASJC Scopus subject areas

  • Surgery
  • Transplantation

引用此

Chou, N. K., Ko, W. J., Chi, N. H., Chen, Y. S., Yu, H. Y., Hsu, R. B., Fang, C. T., Chang, S. C., Lin, F. Y., Chu, S. H., & Wang, S. S. (2006). Sparing Immunosuppression in Heart Transplant Recipients With Severe Sepsis. Transplantation Proceedings, 38(7), 2145-2146. https://doi.org/10.1016/j.transproceed.2006.06.009