Soy isoflavone supplementation in postmenopausal women: Effects on plasma lipids, antioxidant enzyme activities and bone density

研究成果: 雜誌貢獻文章

103 引文 (Scopus)

摘要

OBJECTIVE: To investigate isoflavone supplementation on plasma lipids, erythrocyte antioxidant enzyme activities and bone mineral density in postmenopausal women. STUDY DESIGN: Thirty-seven postmenopausal women were given 150 mg/d of isoflavone supplements twice daily for six months. Blood was sampled before and after supplementation, at three and six months. RESULTS: There were no significant differences in plasma total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride concentrations or erythrocyte antioxidant enzyme activities after three and six months of supplementation when compared with the baseline. No significant changes were noted in calcaneus bone mineral density after supplementing isoflavones for six months. CONCLUSION: The antioxidant effect of isoflavones in normal postmenopausal women is not obvious, and supplementation with isoflavone alone may not have a hypocholesterolemic effect. Since the duration of this study was too short with respect to bone density, longer studies are needed to clarify the bone-sparing effect of isoflavone supplementation.
原文英語
頁(從 - 到)221-226
頁數6
期刊Journal of Reproductive Medicine for the Obstetrician and Gynecologist
46
發行號3
出版狀態已發佈 - 2001

指紋

Isoflavones
Bone Density
Antioxidants
Lipids
Enzymes
Erythrocytes
Calcaneus
LDL Cholesterol
HDL Cholesterol
Cholesterol
Bone and Bones

Keywords

  • Antioxidants
  • Bone density
  • Isoflavones
  • Lipids
  • Postmenopause
  • Soy proteins

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

引用此文

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title = "Soy isoflavone supplementation in postmenopausal women: Effects on plasma lipids, antioxidant enzyme activities and bone density",
abstract = "OBJECTIVE: To investigate isoflavone supplementation on plasma lipids, erythrocyte antioxidant enzyme activities and bone mineral density in postmenopausal women. STUDY DESIGN: Thirty-seven postmenopausal women were given 150 mg/d of isoflavone supplements twice daily for six months. Blood was sampled before and after supplementation, at three and six months. RESULTS: There were no significant differences in plasma total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride concentrations or erythrocyte antioxidant enzyme activities after three and six months of supplementation when compared with the baseline. No significant changes were noted in calcaneus bone mineral density after supplementing isoflavones for six months. CONCLUSION: The antioxidant effect of isoflavones in normal postmenopausal women is not obvious, and supplementation with isoflavone alone may not have a hypocholesterolemic effect. Since the duration of this study was too short with respect to bone density, longer studies are needed to clarify the bone-sparing effect of isoflavone supplementation.",
keywords = "Antioxidants, Bone density, Isoflavones, Lipids, Postmenopause, Soy proteins, Antioxidants, Bone density, Isoflavones, Lipids, Postmenopause, Soy proteins",
author = "Chun-Sen Hsu and Shen, {Winston W.} and Yu-Mei Hsueh and Sung-Ling Yeh",
year = "2001",
language = "English",
volume = "46",
pages = "221--226",
journal = "The Journal of reproductive medicine",
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T1 - Soy isoflavone supplementation in postmenopausal women

T2 - Effects on plasma lipids, antioxidant enzyme activities and bone density

AU - Hsu, Chun-Sen

AU - Shen, Winston W.

AU - Hsueh, Yu-Mei

AU - Yeh, Sung-Ling

PY - 2001

Y1 - 2001

N2 - OBJECTIVE: To investigate isoflavone supplementation on plasma lipids, erythrocyte antioxidant enzyme activities and bone mineral density in postmenopausal women. STUDY DESIGN: Thirty-seven postmenopausal women were given 150 mg/d of isoflavone supplements twice daily for six months. Blood was sampled before and after supplementation, at three and six months. RESULTS: There were no significant differences in plasma total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride concentrations or erythrocyte antioxidant enzyme activities after three and six months of supplementation when compared with the baseline. No significant changes were noted in calcaneus bone mineral density after supplementing isoflavones for six months. CONCLUSION: The antioxidant effect of isoflavones in normal postmenopausal women is not obvious, and supplementation with isoflavone alone may not have a hypocholesterolemic effect. Since the duration of this study was too short with respect to bone density, longer studies are needed to clarify the bone-sparing effect of isoflavone supplementation.

AB - OBJECTIVE: To investigate isoflavone supplementation on plasma lipids, erythrocyte antioxidant enzyme activities and bone mineral density in postmenopausal women. STUDY DESIGN: Thirty-seven postmenopausal women were given 150 mg/d of isoflavone supplements twice daily for six months. Blood was sampled before and after supplementation, at three and six months. RESULTS: There were no significant differences in plasma total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride concentrations or erythrocyte antioxidant enzyme activities after three and six months of supplementation when compared with the baseline. No significant changes were noted in calcaneus bone mineral density after supplementing isoflavones for six months. CONCLUSION: The antioxidant effect of isoflavones in normal postmenopausal women is not obvious, and supplementation with isoflavone alone may not have a hypocholesterolemic effect. Since the duration of this study was too short with respect to bone density, longer studies are needed to clarify the bone-sparing effect of isoflavone supplementation.

KW - Antioxidants

KW - Bone density

KW - Isoflavones

KW - Lipids

KW - Postmenopause

KW - Soy proteins

KW - Antioxidants

KW - Bone density

KW - Isoflavones

KW - Lipids

KW - Postmenopause

KW - Soy proteins

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