Solving the puzzle of pluripotent stem cell-derived cardiomyocyte maturation: Piece by piece

David J. Lundy, Desy S. Lee, Patrick C.H. Hsieh

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

There is a growing need for in vitro models which can serve as platforms for drug screening and basic research. Human adult cardiomyocytes cannot be readily obtained or cultured, and so pluripotent stem cell-derived cardiomyocytes appear to be an attractive option. Unfortunately, these cells are structurally and functionally immature-more comparable to foetal cardiomyocytes than adult. A recent study by Ruan et al., provides new insights into accelerating the maturation process and takes us a step closer to solving the puzzle of pluripotent stem cell-derived cardiomyocyte maturation.
原文英語
文章編號143
期刊Annals of Translational Medicine
5
發行號6
DOIs
出版狀態已發佈 - 三月 1 2017
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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