Size effect of colloidal selenium particles on the inhibition of LPS-induced nitric oxide production

Yue-Hwa Chen, H. P. Chang, Zong Hong Lin, C. R Chris Wang

研究成果: 雜誌貢獻文章同行評審

3 引文 斯高帕斯(Scopus)

摘要

We have stud led the size-dependent inhibition capabilities of colloidal selenium (Se) particles on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells. Four particle sizes of the nano-Se, ranging from 45-220 nm in diameter, were examined. All of them, unlike their bulk material, show clear capabilities of inhibition and a trend dependent on the particles size. The inhbition be comes more potent as the particle size in creases. It indicates that pursuing the reduction of colloidal sizes into nanoscale is not favoured in this biological system.
原文英語
頁(從 - 到)389-393
頁數5
期刊Journal of the Chinese Chemical Society
52
發行號3
出版狀態已發佈 - 2005

ASJC Scopus subject areas

  • Chemistry(all)

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