Silver overlayer-modified surface-enhanced Raman scattering-active gold substrates for potential applications in trace detection of biochemical species

Keng Liang Ou, Ting Chu Hsu, Yu Chuan Liu, Kuang Hsuan Yang, Hui Yen Tsai

研究成果: 雜誌貢獻文章同行評審

7 引文 斯高帕斯(Scopus)

摘要

Because Ag and Au nanoparticles (NPs) possess well-defined localized surface plasmon resonance (LSPR) they are popularly employed in the studies of surface-enhanced Raman scattering (SERS). As shown in the literature and in our previous studies, the advantage of SERS-active Ag NPs is their higher SERS enhancement over Au NPs. On the other hand, the disadvantage of SERS-active Ag NPs compared to Au NPs is their serious decay of SERS enhancement in ambient laboratory air. In this work, we develop a new strategy for preparing highly SERS-active Ag NPs deposited on a roughened Au substrate. This strategy is derived from the modification of electrochemical underpotential deposition (UPD) of metals. The coverage of Ag NPs on the roughened Au substrate can be as high as 0.95. Experimental results indicate that the SERS of Rhodamine 6G (R6G) observed on this developed substrate exhibits a higher intensity by ca. 50-fold of magnitude, as compared with that of R6G observed on the substrate without the deposition of Ag NPs. The limit of detection (LOD) for R6G measured on this substrate is markedly reduced to 2×10-15M. Moreover, aging of SERS effect observed on this developed substrate is significantly depressed, as compared with that observed on a generally prepared SERS-active Ag substrate. These aging tests were performed in an atmosphere of 50% relative humidity (RH) and 20% (v/v) O2 at 30°C for 60 day. Also, the developed SERS-active substrate enables it practically applicable in the trace detection of monosodium urate (MSU)-containing solution in gouty arthritis without a further purification process.

原文英語
頁(從 - 到)188-196
頁數9
期刊Analytica Chimica Acta
806
DOIs
出版狀態已發佈 - 一月 2 2014

ASJC Scopus subject areas

  • 分析化學
  • 生物化學
  • 環境化學
  • 光譜

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