Short-term exposure to particulate matters is associated with septic emboli in infective endocarditis

Fu Chien Hsieh, Chun Yen Huang, Sheng Feng Lin, Jen Tang Sun, Tzung Hai Yen, Chih Chun Chang

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

This survey was to investigate the short-term effect of particulate matters (PMs) exposure on clinical and microbiological variables, especially septic emboli, in infective endocarditis (IE). The study analyzed 138 IE patients in Far Eastern Memorial Hospital from 2005 to 2015 and clinical variables were retrospectively requested. The data of air quality were recorded and collected by a network of 26 monitoring stations spreading in Northern part of Taiwan. We found that IE patients with septic emboli were found to be exposed to a significantly higher level of PM2.5 (32.01 ± 15.89 vs. 21.70 ± 13.05 μg/m, P < .001) and PM10 (54.57 ± 24.43 vs 40.98 ± 24.81 μg/m, P = .002) on lag 0 day when compared to those without. Furthermore, multivariate regression analysis revealed that that ambient exposure to PM2.5 (odds ratio: 3.87, 95% confidence interval: 1.31-8.31; P = .001) and PM10 (odds ratio: 4.58, 95% confidence interval: 2.03-10.32; P < .001) significantly increased risk of septic emboli in IE patients. To our knowledge, this is the first study demonstrating that short-term exposure to PMs was associated with septic emboli in IE.

原文英語
頁(從 - 到)e17899
期刊Medicine
98
發行號45
DOIs
出版狀態已發佈 - 11月 1 2019
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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