Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities

Jin Ding Lin, Pei Ying Lin, Lan Ping Lin, Shang Wei Hsu, Chia Feng Yen, Wen Hui Fang, Sheng Ru Wu, Wu Chien Chien, Ching Hui Loh, Cordia M. Chu

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)

摘要

The aims of the preset study were to describe the profile of serum uric acid, the prevalence of hyperuricemia and its risk factors among children and adolescents with intellectual disabilities. We conducted a cross-sectional study of 941 children and adolescents with intellectual disabilities (aged 4-18 years) who participated in annual health examinations in three special schools in Taiwan. This study indicated 30.6% boys and 17.9% girls with intellectual disabilities were with hyperuricemia in Taiwan. The factors of gender, age and BMI were variables that can significantly predict the hyperuricemia occurrence in this vulnerable population. Those children and adolescents with intellectual disabilities were boys (OR = 2.93, 95% CI = 2.02-4.26) and older age (OR = 6.49, 95% CI = 2.19-19.21) were more likely to be hyperuricemia. With regard to BMI to hyperuricemia occurrence, those children and adolescents with intellectual disabilities were overweight (OR = 1.16-3.21, 95% CI = 1.16-3.21) and being obese (OR = 4.95-11.58, 95% CI = 4.95-11.58) was more likely to have a hyperuricemia than the normal weight group. This study provides the general profile of serum uric acid, hyperuricemia and its risk factors of children and adolescents with intellectual disabilities. Medical professionals should be highly alert to the possible consequences of hyperuricemia and provide useful information about the clinical manifestation of this condition for caregivers of children and adolescents with intellectual disabilities.

原文英語
頁(從 - 到)1481-1489
頁數9
期刊Research in Developmental Disabilities
30
發行號6
DOIs
出版狀態已發佈 - 十一月 1 2009
對外發佈Yes

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Clinical Psychology

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    Lin, J. D., Lin, P. Y., Lin, L. P., Hsu, S. W., Yen, C. F., Fang, W. H., Wu, S. R., Chien, W. C., Loh, C. H., & Chu, C. M. (2009). Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities. Research in Developmental Disabilities, 30(6), 1481-1489. https://doi.org/10.1016/j.ridd.2009.07.008