Serum lipid profiles are associated with semen quality

Chin Yu Liu, Yu Ching Chou, Shyh Hsiang Lin, Sheng Tang Wu, Tai Lung Cha, Hong I. Chen, Chih Wei Tsao

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

摘要

We aimed to explore the associations between different lipid profiles and semen quality in a large-scale general male population. Sperm concentration, total sperm motility, progressive motility, and normal sperm morphology of total 7601 participants were recorded. The association of these semen parameters with the triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein of serum lipid profiles was analyzed. Sperm concentration was statistically positively correlated with triglyceride and very low-density lipoprotein (adjusted P = 0.001 and P = 0.005, respectively). Total sperm motility and progressive motility were statistically increased with increasing low-density lipoprotein and cholesterol levels (both adjusted P = 0.008 and P < 0.001, respectively). The similar J-shaped associations (high-low-low-high) were noted between individual lipid profile and normal sperm morphology, especially low-density lipoprotein and cholesterol with statistical significance (adjusted P = 0.017 and P = 0.021, respectively). The prevalence of abnormal total sperm motility and progressive motility was decreased in participants with high levels of cholesterol (P = 0.008 and P = 0.019, respectively), and the reverse J-shaped associations (low-high-high-low) were noted between high-density lipoprotein, triglyceride, very low-density lipoprotein, and the prevalence of abnormal normal sperm morphology (P = 0.010, P = 0.037, and P = 0.025, respectively). A high cholesterol level was associated with better sperm motility. Similar J-shaped associations were noted between all lipid profiles and normal sperm morphology; meanwhile, the reverse J-shaped trends were identified between them and abnormal normal sperm morphology prevalence.

原文英語
頁(從 - 到)633-638
頁數6
期刊Asian Journal of Andrology
19
發行號6
DOIs
出版狀態已發佈 - 十一月 1 2017

ASJC Scopus subject areas

  • Urology

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  • 引用此

    Liu, C. Y., Chou, Y. C., Lin, S. H., Wu, S. T., Cha, T. L., Chen, H. I., & Tsao, C. W. (2017). Serum lipid profiles are associated with semen quality. Asian Journal of Andrology, 19(6), 633-638. https://doi.org/10.4103/1008-682X.195240