Seroprevalence, seroconversion, and risk factors for toxoplasmosis among pregnant women in Taipei, Taiwan

Ching Sheng Hung, Hung Wen Su, Yu Luen Lee, Hui Wen Weng, Yin Chin Wang, Toshio Naito, Akiko Tsubouchi, Giueng Chueng Wang, Chia-Kwung Fan

研究成果: 雜誌貢獻文章同行評審

10 引文 斯高帕斯(Scopus)


Herein, we determined the seroprevalence, seroconversion, and risk factors associated with Toxoplasma gondii (T. gondii) infection among pregnant women in Taipei, Taiwan. Pregnant women attending antenatal consultation in a Taipei medical center were invited, and 104 women completed a self-administered structured questionnaire. Venous blood samples were collected during the first and third trimester after consent was obtained. Serum IgG and IgM antibodies (Abs) as well as IgG avidity were analyzed using an enzyme-linked fluorescent assay. Of the samples collected in the first trimester, seven were seropositive for IgG Abs and one was seropositive for IgG + IgM Abs with a borderline avidity index, resulting in an overall seroprevalence of 7.7z. No statistically significant association was found between toxoplasmosis and age, pregnancy history, or any risk factors. Seroconversion was not detected from paired sera between the first and third trimesters. Pregnant women with senior high school education level or those who claimed to knowing Toxoplasma exhibited a significantly higher seroprevalence than those with bachelor degree (P = 0.05) or those who claimed not to have this knowledge (P = 0.05). Therefore, failure to understand the importance of T. gondii infection and the prevention measures resulted in the development of toxoplasmosis among these women.
頁(從 - 到)312-317
期刊Japanese Journal of Infectious Diseases
出版狀態已發佈 - 7月 23 2015

ASJC Scopus subject areas

  • 微生物學(醫學)
  • 傳染性疾病


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