Seroprevalence of chlamydia pneumoniae in taiwan

Jen Hsien Wang, Yung Ching Liu, Deh Lin Cheng, Muh Yon Yeng, Yao Shen Chen, Bao Chen Chen

研究成果: 雜誌貢獻文章同行評審

34 引文 斯高帕斯(Scopus)


Chlamydia pneumoniae (TWAR) is a relatively newly discovered respiratory tract pathogen which was first isolated in Taiwan. In order to describe the seroepidemiology of C. pneumoniae in Taiwan, we evaluated 1,085 stored serum samples: 904 from patients, 97 from umbilical cord blood samples, and 84 from medical personnel at the Veterans General Hospital-Kaohsiung, between January 1 and April 30, 1991. Antibodies were determined by the use of a microimmunofluorescence test using elementary bodies of C. pneumoniae AR-39 as antigen. Sera were tested with screening titres of 16 and 512 for immunoglobulin G antibody. The antibody prevalence was found to be 23.1% in young children (6 months to 10 years old), rising to 66.7% in teenagers, and to 96.2% in older age groups. These rates were higher than any reported earlier. The progressively increasing rates of seropositivity found in older individuals indicated a surge of reinfection in these age groups. Only 5 cases were found with micro-IF IgG titres equal to or greater than 512. All were asymptomatic according to the hospital records. In addition to a high prevalence rate in Taiwan, UK data also showed high infection rates in teenagers and elderly people.

頁(從 - 到)565-568
期刊Scandinavian Journal of Infectious Diseases
出版狀態已發佈 - 1993

ASJC Scopus subject areas

  • 微生物學(醫學)
  • 免疫學與微生物學 (全部)
  • 傳染性疾病
  • 免疫學


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