摘要
Chlamydia pneumoniae (TWAR) is a relatively newly discovered respiratory tract pathogen which was first isolated in Taiwan. In order to describe the seroepidemiology of C. pneumoniae in Taiwan, we evaluated 1,085 stored serum samples: 904 from patients, 97 from umbilical cord blood samples, and 84 from medical personnel at the Veterans General Hospital-Kaohsiung, between January 1 and April 30, 1991. Antibodies were determined by the use of a microimmunofluorescence test using elementary bodies of C. pneumoniae AR-39 as antigen. Sera were tested with screening titres of 16 and 512 for immunoglobulin G antibody. The antibody prevalence was found to be 23.1% in young children (6 months to 10 years old), rising to 66.7% in teenagers, and to 96.2% in older age groups. These rates were higher than any reported earlier. The progressively increasing rates of seropositivity found in older individuals indicated a surge of reinfection in these age groups. Only 5 cases were found with micro-IF IgG titres equal to or greater than 512. All were asymptomatic according to the hospital records. In addition to a high prevalence rate in Taiwan, UK data also showed high infection rates in teenagers and elderly people.
原文 | 英語 |
---|---|
頁(從 - 到) | 565-568 |
頁數 | 4 |
期刊 | Scandinavian Journal of Infectious Diseases |
卷 | 25 |
發行號 | 5 |
DOIs | |
出版狀態 | 已發佈 - 1993 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 微生物學(醫學)
- 免疫學與微生物學 (全部)
- 傳染性疾病
- 免疫學