Serological response and persistence in schoolchildren with high baseline seropositive rate after receiving 2009 pandemic influenza A(H1N1) vaccine

Day Yu Chao, Kuang Fu Cheng, Ying Hen Hsieh, Tsai Chung Li, Trong Neng Wu, Chiu Ying Chen, Chen An Tsai, Jin Hwa Chen, Hsien Tsai Chiu, Jang Jih Lu, Mei Chi Su, Yu Hsin Liao

研究成果: 雜誌貢獻文章同行評審

8 引文 斯高帕斯(Scopus)

摘要

The serological response of the current 2009 H1N1 pandemic influenza monovalent vaccine in children exhibiting high baseline seropositive rate was evaluated though a community-based household study. Seroprotection rate of >90% and seroconversion rate of >50% were observed in children one month after receiving the pandemic vaccine. Among children with low baseline antibody titer, a significant lower seroconversion rate (55%) was observed in children who received seasonal trivalent inactivated vaccine (TIV) prior to pandemic vaccine, when compared with those receiving the pandemic vaccine only (86%). Persistence of antibody against the pandemic influenza virus was observed 6 months after vaccination in >80% of children presenting seroprotective antibody levels.

原文英語
頁(從 - 到)617-623
頁數7
期刊Vaccine
29
發行號4
DOIs
出版狀態已發佈 - 一月 17 2011
對外發佈

ASJC Scopus subject areas

  • 分子醫學
  • 免疫學與微生物學 (全部)
  • 獸醫 (全部)
  • 公共衛生、環境和職業健康
  • 傳染性疾病

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