SEN virus infection in patients on peritoneal dialysis

Bang Gee Hsu, Li Yu Wang, Chi Tan Hu, Chih Hsien Wang, Te Chao Fang, Hans Hsienhong Lin

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

◆ Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported. In this study, we determined the prevalence rate of SEN-V viremia in a PD population. ◆ Methods: Serum samples from 47 PD patients and a control group of 43 subjects from the general population at their health examination were assayed for SEN-V-D and -H viremia using polymerase chain reaction. ◆ Results: The proportions of female gender (p = 0.001), previous transfusion (p <0.0001), and higher mean serum AST Level (p = 0.012) were significantly higher in PD patients. The prevalence rates of SEN-V-D and/or -H viremia were not significantly different between PD patients and controls (27.7% vs 32.6%). SEN-V-D(+) patients had lower mean duration of PD than SEN-V(-) patients. Mean ALT level was significantly lower in SEN-V-H(+) than in SEN-V(-) patients (12.8 ± 5.8 vs 19.6 ± 12.1 (IU/L), p = 0.025). None of the SEN-V-infected PD patients had overt clinical or biochemical signs of liver disease. There were no statistically significant differences in prevalence of SEN-V-D and/or -H viremia between automated PD (APD) patients and continuous ambulatory PD (CAPD) patients. ◆ Conclusions: These results indicate that the SEN-V infection rate is not different between healthy individuals and PD patients. Infection with SEN-V is not associated with evident liver disease in PD patients and SEN-V infection rate is not different between APD patients and CAPD patients.

原文英語
頁(從 - 到)74-78
頁數5
期刊Peritoneal Dialysis International
27
發行號1
出版狀態已發佈 - 1月 2007
對外發佈

ASJC Scopus subject areas

  • 腎臟病學

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