摘要
◆ Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported. In this study, we determined the prevalence rate of SEN-V viremia in a PD population. ◆ Methods: Serum samples from 47 PD patients and a control group of 43 subjects from the general population at their health examination were assayed for SEN-V-D and -H viremia using polymerase chain reaction. ◆ Results: The proportions of female gender (p = 0.001), previous transfusion (p <0.0001), and higher mean serum AST Level (p = 0.012) were significantly higher in PD patients. The prevalence rates of SEN-V-D and/or -H viremia were not significantly different between PD patients and controls (27.7% vs 32.6%). SEN-V-D(+) patients had lower mean duration of PD than SEN-V(-) patients. Mean ALT level was significantly lower in SEN-V-H(+) than in SEN-V(-) patients (12.8 ± 5.8 vs 19.6 ± 12.1 (IU/L), p = 0.025). None of the SEN-V-infected PD patients had overt clinical or biochemical signs of liver disease. There were no statistically significant differences in prevalence of SEN-V-D and/or -H viremia between automated PD (APD) patients and continuous ambulatory PD (CAPD) patients. ◆ Conclusions: These results indicate that the SEN-V infection rate is not different between healthy individuals and PD patients. Infection with SEN-V is not associated with evident liver disease in PD patients and SEN-V infection rate is not different between APD patients and CAPD patients.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 74-78 |
| 頁數 | 5 |
| 期刊 | Peritoneal Dialysis International |
| 卷 | 27 |
| 發行號 | 1 |
| 出版狀態 | 已發佈 - 一月 2007 |
| 對外發佈 | Yes |
指紋
ASJC Scopus subject areas
- Nephrology
引用此文
SEN virus infection in patients on peritoneal dialysis. / Hsu, Bang Gee; Wang, Li Yu; Hu, Chi Tan; Wang, Chih Hsien; Fang, Te Chao; Lin, Hans Hsienhong.
於: Peritoneal Dialysis International, 卷 27, 編號 1, 01.2007, p. 74-78.研究成果: 雜誌貢獻 › 文章
}
TY - JOUR
T1 - SEN virus infection in patients on peritoneal dialysis
AU - Hsu, Bang Gee
AU - Wang, Li Yu
AU - Hu, Chi Tan
AU - Wang, Chih Hsien
AU - Fang, Te Chao
AU - Lin, Hans Hsienhong
PY - 2007/1
Y1 - 2007/1
N2 - ◆ Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported. In this study, we determined the prevalence rate of SEN-V viremia in a PD population. ◆ Methods: Serum samples from 47 PD patients and a control group of 43 subjects from the general population at their health examination were assayed for SEN-V-D and -H viremia using polymerase chain reaction. ◆ Results: The proportions of female gender (p = 0.001), previous transfusion (p <0.0001), and higher mean serum AST Level (p = 0.012) were significantly higher in PD patients. The prevalence rates of SEN-V-D and/or -H viremia were not significantly different between PD patients and controls (27.7% vs 32.6%). SEN-V-D(+) patients had lower mean duration of PD than SEN-V(-) patients. Mean ALT level was significantly lower in SEN-V-H(+) than in SEN-V(-) patients (12.8 ± 5.8 vs 19.6 ± 12.1 (IU/L), p = 0.025). None of the SEN-V-infected PD patients had overt clinical or biochemical signs of liver disease. There were no statistically significant differences in prevalence of SEN-V-D and/or -H viremia between automated PD (APD) patients and continuous ambulatory PD (CAPD) patients. ◆ Conclusions: These results indicate that the SEN-V infection rate is not different between healthy individuals and PD patients. Infection with SEN-V is not associated with evident liver disease in PD patients and SEN-V infection rate is not different between APD patients and CAPD patients.
AB - ◆ Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported. In this study, we determined the prevalence rate of SEN-V viremia in a PD population. ◆ Methods: Serum samples from 47 PD patients and a control group of 43 subjects from the general population at their health examination were assayed for SEN-V-D and -H viremia using polymerase chain reaction. ◆ Results: The proportions of female gender (p = 0.001), previous transfusion (p <0.0001), and higher mean serum AST Level (p = 0.012) were significantly higher in PD patients. The prevalence rates of SEN-V-D and/or -H viremia were not significantly different between PD patients and controls (27.7% vs 32.6%). SEN-V-D(+) patients had lower mean duration of PD than SEN-V(-) patients. Mean ALT level was significantly lower in SEN-V-H(+) than in SEN-V(-) patients (12.8 ± 5.8 vs 19.6 ± 12.1 (IU/L), p = 0.025). None of the SEN-V-infected PD patients had overt clinical or biochemical signs of liver disease. There were no statistically significant differences in prevalence of SEN-V-D and/or -H viremia between automated PD (APD) patients and continuous ambulatory PD (CAPD) patients. ◆ Conclusions: These results indicate that the SEN-V infection rate is not different between healthy individuals and PD patients. Infection with SEN-V is not associated with evident liver disease in PD patients and SEN-V infection rate is not different between APD patients and CAPD patients.
KW - Prevalence
KW - SEN virus
UR - http://www.scopus.com/inward/record.url?scp=33947099381&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33947099381&partnerID=8YFLogxK
M3 - Article
C2 - 17179515
AN - SCOPUS:33947099381
VL - 27
SP - 74
EP - 78
JO - Peritoneal Dialysis International
JF - Peritoneal Dialysis International
SN - 0896-8608
IS - 1
ER -