Selective laser sintering of a hydroxyapatite-silica scaffold on cultured MG63 osteoblasts in vitro

Fwu Hsing Liu, Yung Kang Shen, Jeou Long Lee

研究成果: 雜誌貢獻文章同行評審

48 引文 斯高帕斯(Scopus)

摘要

This study forms hydroxyapatite-silica ceramic structure, which can generate interconnected porous 3D models suitable as bone scaffold, using a novel selective laser sintering (SLS) technique. Hydroxyapatite (HA) powder and a silica sol are first mixed into slurries. After processing by SLS, the HA particles are embedded in the gelled silica matrix to form green parts. The processed parts are analyzed by scanning electron microscopy (SEM). The number of cells attached on this scaffold surface is obtained by the in vitro cultured cells test. The higher number of viable cells are obtained when the sintering temperature of the scaffold was 1200°C at day 4 of cell culturing. The proposed technology can be applied to generate a bone scaffold model of porous bio-ceramics for biomedicine.
原文英語
頁(從 - 到)439-444
頁數6
期刊International Journal of Precision Engineering and Manufacturing
13
發行號3
DOIs
出版狀態已發佈 - 三月 2012

ASJC Scopus subject areas

  • 電氣與電子工程
  • 工業與製造工程
  • 機械工業

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