Roles of Resveratrol as Signaling Sensor and Gatekeeper

Ya-Jung Shih, Yi Ru Chen, Kuan Wang, Jacqueline Whang-Peng, Heng Yuan Tang, Hung-Yun Lin, Paul J. Davis

研究成果: 書貢獻/報告類型章節(同行評審)

摘要

Resveratrol (trans-3,4′,5-trihydroxystilbene) is a natural phytoalexin that has pharmacological effects on several human diseases: cancer, coronary artery disease and neurodegenerative diseases. Many studies have reported the application of resveratrol as a preventive drug for these important conditions. In addition, recent reports indicate that resveratrol may also increase the lifespan of yeast and fruit flies. The positive effects of resveratrol have largely been demonstrated in vitro or in animal studies, with only limited and inconsistent effects reported in clinical studies. In addition, roles of resveratrol as signaling sensor and gatekeeper are still not clear. In this chapter, we will summarize a group of potentially important roles for resveratrol in diverse biological systems, particularly in metabolism and in cancer.
原文英語
主出版物標題Resveratrol: State-of-the-Art Science and Health Applications
發行者World Scientific Publishing Co.
頁面115-144
出版狀態已發佈 - 2018

指紋

Diptera
Neurodegenerative Diseases
resveratrol
Coronary Artery Disease
Fruit
Neoplasms
Yeasts
Pharmacology
Pharmaceutical Preparations
In Vitro Techniques
Clinical Studies
phytoalexins

引用此文

Shih, Y-J., Chen, Y. R., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H-Y., & Davis, P. J. (2018). Roles of Resveratrol as Signaling Sensor and Gatekeeper. 於 Resveratrol: State-of-the-Art Science and Health Applications (頁 115-144). World Scientific Publishing Co..

Roles of Resveratrol as Signaling Sensor and Gatekeeper. / Shih, Ya-Jung; Chen, Yi Ru; Wang, Kuan; Whang-Peng, Jacqueline; Tang, Heng Yuan; Lin, Hung-Yun; Davis, Paul J.

Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., 2018. p. 115-144.

研究成果: 書貢獻/報告類型章節(同行評審)

Shih, Y-J, Chen, YR, Wang, K, Whang-Peng, J, Tang, HY, Lin, H-Y & Davis, PJ 2018, Roles of Resveratrol as Signaling Sensor and Gatekeeper. 於 Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., 頁 115-144.
Shih Y-J, Chen YR, Wang K, Whang-Peng J, Tang HY, Lin H-Y 等. Roles of Resveratrol as Signaling Sensor and Gatekeeper. 於 Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co. 2018. p. 115-144
Shih, Ya-Jung ; Chen, Yi Ru ; Wang, Kuan ; Whang-Peng, Jacqueline ; Tang, Heng Yuan ; Lin, Hung-Yun ; Davis, Paul J. / Roles of Resveratrol as Signaling Sensor and Gatekeeper. Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., 2018. 頁 115-144
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abstract = "Resveratrol (trans-3,4′,5-trihydroxystilbene) is a natural phytoalexin that has pharmacological effects on several human diseases: cancer, coronary artery disease and neurodegenerative diseases. Many studies have reported the application of resveratrol as a preventive drug for these important conditions. In addition, recent reports indicate that resveratrol may also increase the lifespan of yeast and fruit flies. The positive effects of resveratrol have largely been demonstrated in vitro or in animal studies, with only limited and inconsistent effects reported in clinical studies. In addition, roles of resveratrol as signaling sensor and gatekeeper are still not clear. In this chapter, we will summarize a group of potentially important roles for resveratrol in diverse biological systems, particularly in metabolism and in cancer.",
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T1 - Roles of Resveratrol as Signaling Sensor and Gatekeeper

AU - Shih, Ya-Jung

AU - Chen, Yi Ru

AU - Wang, Kuan

AU - Whang-Peng, Jacqueline

AU - Tang, Heng Yuan

AU - Lin, Hung-Yun

AU - Davis, Paul J.

PY - 2018

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N2 - Resveratrol (trans-3,4′,5-trihydroxystilbene) is a natural phytoalexin that has pharmacological effects on several human diseases: cancer, coronary artery disease and neurodegenerative diseases. Many studies have reported the application of resveratrol as a preventive drug for these important conditions. In addition, recent reports indicate that resveratrol may also increase the lifespan of yeast and fruit flies. The positive effects of resveratrol have largely been demonstrated in vitro or in animal studies, with only limited and inconsistent effects reported in clinical studies. In addition, roles of resveratrol as signaling sensor and gatekeeper are still not clear. In this chapter, we will summarize a group of potentially important roles for resveratrol in diverse biological systems, particularly in metabolism and in cancer.

AB - Resveratrol (trans-3,4′,5-trihydroxystilbene) is a natural phytoalexin that has pharmacological effects on several human diseases: cancer, coronary artery disease and neurodegenerative diseases. Many studies have reported the application of resveratrol as a preventive drug for these important conditions. In addition, recent reports indicate that resveratrol may also increase the lifespan of yeast and fruit flies. The positive effects of resveratrol have largely been demonstrated in vitro or in animal studies, with only limited and inconsistent effects reported in clinical studies. In addition, roles of resveratrol as signaling sensor and gatekeeper are still not clear. In this chapter, we will summarize a group of potentially important roles for resveratrol in diverse biological systems, particularly in metabolism and in cancer.

M3 - Chapter (peer-reviewed)

SP - 115

EP - 144

BT - Resveratrol: State-of-the-Art Science and Health Applications

PB - World Scientific Publishing Co.

ER -