Roles of EBUS-TBNA in non-small cell lung cancer

Fu Tsai Chung, Chih Hsi Kuo, Hao Cheng Chen, Po Hao Feng, Shu Min Lin, Chih Ten Yu, Chien Ying Liu, Chih Wei Wang, Han Pin Kuo

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Background: Endobronchial ultrasound-guided transbronchial aspiration (EBUSTBNA) has the potential to improve nodal diagnosis and staging in non-small cell lung cancer (NSCLC). This study was performed to explore the roles of EBUS-TBNA in NSCLC. Methods: From2007 to 2009, 164 NSCLC patientswere examined by EBUS-TBNA. The patients were divided into a diagnosis group (n = 64) and a staging group (n = 100). Results: For all patients, the diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were 92.3%, 100%, 100%, 88.2%, and 95.1%, respectively. In the diagnosis group, the diagnostic sensitivity, specificity, PPV, NPV, and accuracy were 89.7%, 100%, 100%, 86.2%, and 94.4%, respectively. Thirty five patients (54.7%) positive for malignancy as determined by EBUS-TBNA avoided surgery. In the staging group, the diagnostic sensitivity, specificity,PPV,NPV, accuracy, and surgery avoidance rate were 93.8%, 100%, 100%, 89.7%, 96%, and 61%, respectively. Conclusions: EBUS-TBNA is a feasible and effective tool for NSCLC diagnosis and staging that also reduces surgery rates. Patients with NSCLC should initially undergo the less invasive EBUS-TBNA procedure for diagnosis and staging of NSCLC.However, negative findingsmust be confirmed by surgery.
原文英語
頁(從 - 到)182-187
頁數6
期刊Thoracic Cancer
3
發行號2
DOIs
出版狀態已發佈 - 5月 2012
對外發佈

ASJC Scopus subject areas

  • 腫瘤科
  • 肺和呼吸系統醫學

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