Role of calmodulin/protein kinase C in interferon production by poly(rI) · poly(rC) in primed human cell cultures

H. Y. Lin, H. R. Thacore

研究成果: 雜誌貢獻文章

3 引文 (Scopus)

摘要

Human cells treated with trifluoperazine (TFP) or K252a prior to and/or during priming with human interferon-α (HuIFN-α) produce significantly more IFN on induction with poly(rI) · poly(rC) than primed cells in the absence of the drug. Results suggest that calmodulin/protein kinase activity may be involved in priming activity of HuIFN-α.
原文英語
頁(從 - 到)375-378
頁數4
期刊Journal of Interferon Research
10
發行號4
出版狀態已發佈 - 1990
對外發佈Yes

指紋

Poly I-C
Calcium-Calmodulin-Dependent Protein Kinases
Protein Kinase C
Interferons
Cell Culture Techniques
Trifluoperazine
Human Activities
Protein Kinases
Pharmaceutical Preparations
staurosporine aglycone

ASJC Scopus subject areas

  • Immunology
  • Virology

引用此文

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abstract = "Human cells treated with trifluoperazine (TFP) or K252a prior to and/or during priming with human interferon-α (HuIFN-α) produce significantly more IFN on induction with poly(rI) · poly(rC) than primed cells in the absence of the drug. Results suggest that calmodulin/protein kinase activity may be involved in priming activity of HuIFN-α.",
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AU - Thacore, H. R.

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N2 - Human cells treated with trifluoperazine (TFP) or K252a prior to and/or during priming with human interferon-α (HuIFN-α) produce significantly more IFN on induction with poly(rI) · poly(rC) than primed cells in the absence of the drug. Results suggest that calmodulin/protein kinase activity may be involved in priming activity of HuIFN-α.

AB - Human cells treated with trifluoperazine (TFP) or K252a prior to and/or during priming with human interferon-α (HuIFN-α) produce significantly more IFN on induction with poly(rI) · poly(rC) than primed cells in the absence of the drug. Results suggest that calmodulin/protein kinase activity may be involved in priming activity of HuIFN-α.

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