Risk factors for sudden cardiac death among patients with schizophrenia

Ping Yi Hou, Galen Chin Lun Hung, Jia Rong Jhong, Shang Ying Tsai, Chiao Chicy Chen, Chian Jue Kuo

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

摘要

Introduction: Patients with schizophrenia suffer from excessive premature mortality, and sudden cardiac death (SCD) is receiving growing attention as a potential cause. Aim: The present study investigated the incidence of SCD and its risk factors in a large schizophrenia cohort. Methods: We enrolled a consecutive series of 8264 patients diagnosed with schizophrenia (according to DSM-III-R and DSM-IV criteria) who were admitted to a psychiatric center in northern Taiwan from January 1, 1985 through December 31, 2008. By linking with national mortality database, 64 cases of SCD were identified. The standardized mortality ratio (SMR) for SCD was estimated. The cases were matched with controls randomly selected using risk-set sampling in a 1:2 ratio. A standardized chart review process was used to collect socio-demographic and clinical characteristics and the prescribed drugs for each study subject. Multivariate conditional logistic regression analysis was used to identify correlates of SCD at the index admission and the latest admission. Results: The SMR for SCD was 4.5. For the clinical profiles at the index admission, physical disease (adjusted risk ratio [aRR] = 2.91, P

原文英語
文章編號6488
頁(從 - 到)395-401
頁數7
期刊Schizophrenia Research
168
發行號1-2
DOIs
出版狀態已發佈 - 十月 1 2015

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

指紋 深入研究「Risk factors for sudden cardiac death among patients with schizophrenia」主題。共同形成了獨特的指紋。

  • 引用此

    Hou, P. Y., Hung, G. C. L., Jhong, J. R., Tsai, S. Y., Chen, C. C., & Kuo, C. J. (2015). Risk factors for sudden cardiac death among patients with schizophrenia. Schizophrenia Research, 168(1-2), 395-401. [6488]. https://doi.org/10.1016/j.schres.2015.07.015