摘要
Information is lacking on the integrated evaluation of mortality rates in healthcare-associated infections (HAIs). Our aim was to differentiate the risk factors responsible for the incidence from those for the case-fatality rates in association with HAIs. We therefore examined the time trends of both incidence and case-fatality rates over a 20-year period at a tertiary-care teaching medical centre in Taiwan and the mortality rate was expressed as the product of the incidence rate and the case-fatality rate. During the study period the overall mortality rate fell from 0 46 to 0 32 deaths/1000 patient-days and the incidence rate fell from 3 41 to 2 31/1000 patient-days, but the case-fatality rate increased marginally from 13 5% to 14 0%. The independent risk factors associated with incidence of HAIs were age, gender, infection site, admission type, and department of hospitalization. Significant prognostic factors for HAI case-fatality were age, infection site, intensive care, and clinical department. We conclude that the decreasing trend for the HAI mortality rate was accompanied by a significant decline in the incidence rate and this was offset by a slightly increasing trend in the case-fatality rate. This deconstruction approach could provide further insights into the underlying complex causes of mortality for HAIs.
原文 | 英語 |
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頁(從 - 到) | 198-206 |
頁數 | 9 |
期刊 | Epidemiology and Infection |
卷 | 144 |
發行號 | 1 |
DOIs | |
出版狀態 | 已發佈 - 1月 1 2016 |
ASJC Scopus subject areas
- 流行病學
- 醫藥 (全部)
- 傳染性疾病