Risk factors correlated with risk of insulin resistance using homeostasis model assessment in adolescents in Taiwan

Shiyng-Yu Lin, Chien-Tien Su, Yi-Chen Hsieh, Yu Ling Li, Yih Ru Chen, Shu Yun Cheng, Chien Ming Hu, Yi-Hua Chen, Fang-I Hsieh, Hung-Yi Chiou

研究成果: 雜誌貢獻文章

2 引文 (Scopus)

摘要

The study aims to discover risk factors significantly correlated with insulin resistance among adolescents in Taiwan. A total of 339 study subjects were recruited in this cross-sectional study. A self-administered questionnaire and physical examinations including anthropometrics and biochemistry profiles were collected. Insulin resistance was assessed using homeostasis model assessment for insulin resistance (HOMA-IR). Study subjects had a significantly increased risk of IR for those with abnormal level of body mass index (odds ratio [OR] = 3.54; 95% confidence interval [CI] = 1.81-6.91), body fat (OR = 2.71; 95% CI = 1.25-5.88), and waist circumference (OR = 25.04; 95% CI = 2.93-214.14) when compared with those who have normal values. Furthermore, a significantly joint effect of 10.86-fold risk for HOMA-IR abnormality among body fat, body mass index, and systolic blood pressure was observed. The identification of risk factors significantly correlated with IR will be important to prevent metabolic syndrome-related diseases and complications for adolescents in their future life.
原文英語
頁(從 - 到)NP476-NP484
期刊Asia-Pacific Journal of Public Health
27
發行號2
DOIs
出版狀態已發佈 - 三月 4 2015

指紋

Taiwan
Insulin Resistance
Homeostasis
Odds Ratio
Confidence Intervals
Adipose Tissue
Body Mass Index
Blood Pressure
Fat Body
Waist Circumference
Biochemistry
Physical Examination
Reference Values
Cross-Sectional Studies

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

引用此文

@article{fd2f195d62cb418e853c733e0d61d130,
title = "Risk factors correlated with risk of insulin resistance using homeostasis model assessment in adolescents in Taiwan",
abstract = "The study aims to discover risk factors significantly correlated with insulin resistance among adolescents in Taiwan. A total of 339 study subjects were recruited in this cross-sectional study. A self-administered questionnaire and physical examinations including anthropometrics and biochemistry profiles were collected. Insulin resistance was assessed using homeostasis model assessment for insulin resistance (HOMA-IR). Study subjects had a significantly increased risk of IR for those with abnormal level of body mass index (odds ratio [OR] = 3.54; 95{\%} confidence interval [CI] = 1.81-6.91), body fat (OR = 2.71; 95{\%} CI = 1.25-5.88), and waist circumference (OR = 25.04; 95{\%} CI = 2.93-214.14) when compared with those who have normal values. Furthermore, a significantly joint effect of 10.86-fold risk for HOMA-IR abnormality among body fat, body mass index, and systolic blood pressure was observed. The identification of risk factors significantly correlated with IR will be important to prevent metabolic syndrome-related diseases and complications for adolescents in their future life.",
keywords = "adolescents, HOMA-IR, insulin resistance, metabolic syndrome, risk factors",
author = "Shiyng-Yu Lin and Chien-Tien Su and Yi-Chen Hsieh and Li, {Yu Ling} and Chen, {Yih Ru} and Cheng, {Shu Yun} and Hu, {Chien Ming} and Yi-Hua Chen and Fang-I Hsieh and Hung-Yi Chiou",
year = "2015",
month = "3",
day = "4",
doi = "10.1177/1010539512471075",
language = "English",
volume = "27",
pages = "NP476--NP484",
journal = "Asia-Pacific Journal of Public Health",
issn = "1010-5395",
publisher = "SAGE Publications Inc.",
number = "2",

}

TY - JOUR

T1 - Risk factors correlated with risk of insulin resistance using homeostasis model assessment in adolescents in Taiwan

AU - Lin, Shiyng-Yu

AU - Su, Chien-Tien

AU - Hsieh, Yi-Chen

AU - Li, Yu Ling

AU - Chen, Yih Ru

AU - Cheng, Shu Yun

AU - Hu, Chien Ming

AU - Chen, Yi-Hua

AU - Hsieh, Fang-I

AU - Chiou, Hung-Yi

PY - 2015/3/4

Y1 - 2015/3/4

N2 - The study aims to discover risk factors significantly correlated with insulin resistance among adolescents in Taiwan. A total of 339 study subjects were recruited in this cross-sectional study. A self-administered questionnaire and physical examinations including anthropometrics and biochemistry profiles were collected. Insulin resistance was assessed using homeostasis model assessment for insulin resistance (HOMA-IR). Study subjects had a significantly increased risk of IR for those with abnormal level of body mass index (odds ratio [OR] = 3.54; 95% confidence interval [CI] = 1.81-6.91), body fat (OR = 2.71; 95% CI = 1.25-5.88), and waist circumference (OR = 25.04; 95% CI = 2.93-214.14) when compared with those who have normal values. Furthermore, a significantly joint effect of 10.86-fold risk for HOMA-IR abnormality among body fat, body mass index, and systolic blood pressure was observed. The identification of risk factors significantly correlated with IR will be important to prevent metabolic syndrome-related diseases and complications for adolescents in their future life.

AB - The study aims to discover risk factors significantly correlated with insulin resistance among adolescents in Taiwan. A total of 339 study subjects were recruited in this cross-sectional study. A self-administered questionnaire and physical examinations including anthropometrics and biochemistry profiles were collected. Insulin resistance was assessed using homeostasis model assessment for insulin resistance (HOMA-IR). Study subjects had a significantly increased risk of IR for those with abnormal level of body mass index (odds ratio [OR] = 3.54; 95% confidence interval [CI] = 1.81-6.91), body fat (OR = 2.71; 95% CI = 1.25-5.88), and waist circumference (OR = 25.04; 95% CI = 2.93-214.14) when compared with those who have normal values. Furthermore, a significantly joint effect of 10.86-fold risk for HOMA-IR abnormality among body fat, body mass index, and systolic blood pressure was observed. The identification of risk factors significantly correlated with IR will be important to prevent metabolic syndrome-related diseases and complications for adolescents in their future life.

KW - adolescents

KW - HOMA-IR

KW - insulin resistance

KW - metabolic syndrome

KW - risk factors

UR - http://www.scopus.com/inward/record.url?scp=84926345811&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84926345811&partnerID=8YFLogxK

U2 - 10.1177/1010539512471075

DO - 10.1177/1010539512471075

M3 - Article

VL - 27

SP - NP476-NP484

JO - Asia-Pacific Journal of Public Health

JF - Asia-Pacific Journal of Public Health

SN - 1010-5395

IS - 2

ER -