Retinoblastoma with spinal recurrence presenting as spinal cord compression

Chia Yau Chang, Giun Yi Hung, Wen-Ming Hsu, Shu Ching Kao, Betau Hwang, Yuh Lin Hsieh

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

摘要

Central nervous system (CNS) involvement is not rare in extraocular retinoblastoma, and it is not surprising to find it in view of its route of spread. However, although spinal recurrence presenting as spinal cord compression (SCC) is a form of CNS involvement, it is extremely rare. This report describes two patients with unilateral retinoblastoma with spinal recurrence presenting as SCC. The first patient developed erythematous swelling of the right foot and weakness of the bilateral lower limbs at 7 months after left enucleation. Examination revealed pitting edema of bilateral feet and muscle power of 2+ to 3+, with intact sensory function. The second patient developed weakness of the bilateral lower limbs, and defecative and urinary difficulty for 2 days at 8 months after left enucleation. Examination revealed pitting edema of bilateral feet and muscle power of 2+, with defective sensory function. Both patients received surgery and local irradiation after SCC. The first patient refused chemotherapy and survived only 4 months due to disease progression. The second patient received systemic and intrathecal chemotherapy, and survived 19.5 months without disease progression. Spinal recurrence with SCC should be suspected when leg weakness or bowel or bladder disturbance occurs in patients with retinoblastoma.

原文英語
頁(從 - 到)497-502
頁數6
期刊Journal of the Formosan Medical Association
105
發行號6
DOIs
出版狀態已發佈 - 一月 1 2006
對外發佈Yes

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ASJC Scopus subject areas

  • Medicine(all)

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