Report of invasive Rhodococcus equi infections in Taiwan, with an emphasis on the emergence of multidrug-resistant strains

Po Ren Hsueh, Chien Ching Hung, Lee Jeng Teng, Ming Chih Yu, Yu Chi Chen, Hua Kung Wang, Kwen Tay Luh

研究成果: 雜誌貢獻文章同行評審

35 引文 斯高帕斯(Scopus)

摘要

From November 1995 to October 1997, seven patients with invasive infections due to Rhodococcus equi were treated in Taiwan. Four patients had pulmonary lesions, and one each of the remaining three patients had a recurrent Port-A-Cath (Kabi-Pharmacia, North Ryde, New South Wales, Australia)- related bacteremia, a primary bacteremia, and a brain abscess. Three patients had underlying hematologic malignancies, and one each of the remaining four patients had diabetes mellitus, Waldenstrom's macroglobulinemia, long-term use of steroids, and AIDS. The 13 isolates of R. equi recovered from these patients were identified by using API Coryne System (bioMerieux, Marcy l'Etoile, France), VITEK GPI card (bioMerieux Vitek, Hazelwood, MO), supplemental biochemical tests, and cellular fatty acid chromatograms. Susceptibilities of these isolates to 16 antimicrobial agents, with use of the agar dilution method, varied; among them, amikacin and trimethoprim-sulfamethoxazole were the most active agents. Different random amplified polymorphic DNA (RAPD) patterns of isolates from different patients documented the lack of epidemiological relatedness of the causative organisms of these infections. This study confirms the emergence of multidrug- resistant R. equi infection in Taiwan and documents the relapsing or reactivating nature of this infection.

原文英語
頁(從 - 到)370-375
頁數6
期刊Clinical Infectious Diseases
27
發行號2
出版狀態已發佈 - 1998
對外發佈

ASJC Scopus subject areas

  • 免疫學

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