Repeated and multiple new vertebral compression fractures after percutaneous transpedicular vertebroplasty

Yuan Y. Tseng, Tao Chieh Yang, Po Hsun Tu, Yang L. Lo, Shun T. Yang

研究成果: 雜誌貢獻文章

50 引文 (Scopus)

摘要

STUDY DESIGN. A retrospective study to detect patients with new-onset compression fractures following vertebroplasty. OBJECTIVE. To investigate the characteristics and associated risk factors of new-onset vertebral compression fractures after vertebroplasty. SUMMARY OF BACKGROUND DATA. Percutaneous vertebroplasty is a well-established technique for treating osteoporotic compression fractures. Short-term results are promising, but longer-term studies have suggested a possible accelerated failure rate in the adjacent vertebral body. METHODS. We retrospectively reviewed patients with osteoporotic compression fractures from January 2000 to June 2006. The patients received percutaneous vertebroplasty with bone cement augmentation. Long-term follow-up radiographically identified the occurrence of vertebral fracture (minimum follow-up 24 months) after an initial vertebral fracture. RESULTS. In 852 patients (1131 vertebrae), 58.8% to 63.8% of new compression fractures after vertebroplasty were adjacent compression fractures. Adjacent fractures occurred much sooner than nonadjacent fractures; (71.9 ± 71.8 days vs. 286.8 ± 232.8 days, P <0.001). In patients who experienced vertebral compression fractures 2 or more times, older age, lower baseline bone mineral density (BMD), and more pre-existing vertebral compression fractures were demonstrated in this study (P <0.005). The gender and amount of cemented polymethyl methacrylate were not statistically different between Groups A (1 vertebral compression fracture) and B (vertebral compression fracture ≥2 times). CONCLUSION. New-onset vertebral compression fractures occurred repeatedly within a few years after vertebroplasty. New-onset adjacent-level fractures occurred sooner and were more predominate than nonadjacent level fractures. The results of this study suggest that older patient age, lower baseline BMD, and more pre-existing vertebral fractures were found to be risk factors for multiple vertebral compression fractures.

原文英語
頁(從 - 到)1917-1922
頁數6
期刊Spine
34
發行號18
DOIs
出版狀態已發佈 - 八月 2009

指紋

Vertebroplasty
Compression Fractures
Osteoporotic Fractures
Bone Density
Bone Cements
Polymethyl Methacrylate

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

引用此文

Repeated and multiple new vertebral compression fractures after percutaneous transpedicular vertebroplasty. / Tseng, Yuan Y.; Yang, Tao Chieh; Tu, Po Hsun; Lo, Yang L.; Yang, Shun T.

於: Spine, 卷 34, 編號 18, 08.2009, p. 1917-1922.

研究成果: 雜誌貢獻文章

Tseng, Yuan Y. ; Yang, Tao Chieh ; Tu, Po Hsun ; Lo, Yang L. ; Yang, Shun T. / Repeated and multiple new vertebral compression fractures after percutaneous transpedicular vertebroplasty. 於: Spine. 2009 ; 卷 34, 編號 18. 頁 1917-1922.
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title = "Repeated and multiple new vertebral compression fractures after percutaneous transpedicular vertebroplasty",
abstract = "STUDY DESIGN. A retrospective study to detect patients with new-onset compression fractures following vertebroplasty. OBJECTIVE. To investigate the characteristics and associated risk factors of new-onset vertebral compression fractures after vertebroplasty. SUMMARY OF BACKGROUND DATA. Percutaneous vertebroplasty is a well-established technique for treating osteoporotic compression fractures. Short-term results are promising, but longer-term studies have suggested a possible accelerated failure rate in the adjacent vertebral body. METHODS. We retrospectively reviewed patients with osteoporotic compression fractures from January 2000 to June 2006. The patients received percutaneous vertebroplasty with bone cement augmentation. Long-term follow-up radiographically identified the occurrence of vertebral fracture (minimum follow-up 24 months) after an initial vertebral fracture. RESULTS. In 852 patients (1131 vertebrae), 58.8{\%} to 63.8{\%} of new compression fractures after vertebroplasty were adjacent compression fractures. Adjacent fractures occurred much sooner than nonadjacent fractures; (71.9 ± 71.8 days vs. 286.8 ± 232.8 days, P <0.001). In patients who experienced vertebral compression fractures 2 or more times, older age, lower baseline bone mineral density (BMD), and more pre-existing vertebral compression fractures were demonstrated in this study (P <0.005). The gender and amount of cemented polymethyl methacrylate were not statistically different between Groups A (1 vertebral compression fracture) and B (vertebral compression fracture ≥2 times). CONCLUSION. New-onset vertebral compression fractures occurred repeatedly within a few years after vertebroplasty. New-onset adjacent-level fractures occurred sooner and were more predominate than nonadjacent level fractures. The results of this study suggest that older patient age, lower baseline BMD, and more pre-existing vertebral fractures were found to be risk factors for multiple vertebral compression fractures.",
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T1 - Repeated and multiple new vertebral compression fractures after percutaneous transpedicular vertebroplasty

AU - Tseng, Yuan Y.

AU - Yang, Tao Chieh

AU - Tu, Po Hsun

AU - Lo, Yang L.

AU - Yang, Shun T.

PY - 2009/8

Y1 - 2009/8

N2 - STUDY DESIGN. A retrospective study to detect patients with new-onset compression fractures following vertebroplasty. OBJECTIVE. To investigate the characteristics and associated risk factors of new-onset vertebral compression fractures after vertebroplasty. SUMMARY OF BACKGROUND DATA. Percutaneous vertebroplasty is a well-established technique for treating osteoporotic compression fractures. Short-term results are promising, but longer-term studies have suggested a possible accelerated failure rate in the adjacent vertebral body. METHODS. We retrospectively reviewed patients with osteoporotic compression fractures from January 2000 to June 2006. The patients received percutaneous vertebroplasty with bone cement augmentation. Long-term follow-up radiographically identified the occurrence of vertebral fracture (minimum follow-up 24 months) after an initial vertebral fracture. RESULTS. In 852 patients (1131 vertebrae), 58.8% to 63.8% of new compression fractures after vertebroplasty were adjacent compression fractures. Adjacent fractures occurred much sooner than nonadjacent fractures; (71.9 ± 71.8 days vs. 286.8 ± 232.8 days, P <0.001). In patients who experienced vertebral compression fractures 2 or more times, older age, lower baseline bone mineral density (BMD), and more pre-existing vertebral compression fractures were demonstrated in this study (P <0.005). The gender and amount of cemented polymethyl methacrylate were not statistically different between Groups A (1 vertebral compression fracture) and B (vertebral compression fracture ≥2 times). CONCLUSION. New-onset vertebral compression fractures occurred repeatedly within a few years after vertebroplasty. New-onset adjacent-level fractures occurred sooner and were more predominate than nonadjacent level fractures. The results of this study suggest that older patient age, lower baseline BMD, and more pre-existing vertebral fractures were found to be risk factors for multiple vertebral compression fractures.

AB - STUDY DESIGN. A retrospective study to detect patients with new-onset compression fractures following vertebroplasty. OBJECTIVE. To investigate the characteristics and associated risk factors of new-onset vertebral compression fractures after vertebroplasty. SUMMARY OF BACKGROUND DATA. Percutaneous vertebroplasty is a well-established technique for treating osteoporotic compression fractures. Short-term results are promising, but longer-term studies have suggested a possible accelerated failure rate in the adjacent vertebral body. METHODS. We retrospectively reviewed patients with osteoporotic compression fractures from January 2000 to June 2006. The patients received percutaneous vertebroplasty with bone cement augmentation. Long-term follow-up radiographically identified the occurrence of vertebral fracture (minimum follow-up 24 months) after an initial vertebral fracture. RESULTS. In 852 patients (1131 vertebrae), 58.8% to 63.8% of new compression fractures after vertebroplasty were adjacent compression fractures. Adjacent fractures occurred much sooner than nonadjacent fractures; (71.9 ± 71.8 days vs. 286.8 ± 232.8 days, P <0.001). In patients who experienced vertebral compression fractures 2 or more times, older age, lower baseline bone mineral density (BMD), and more pre-existing vertebral compression fractures were demonstrated in this study (P <0.005). The gender and amount of cemented polymethyl methacrylate were not statistically different between Groups A (1 vertebral compression fracture) and B (vertebral compression fracture ≥2 times). CONCLUSION. New-onset vertebral compression fractures occurred repeatedly within a few years after vertebroplasty. New-onset adjacent-level fractures occurred sooner and were more predominate than nonadjacent level fractures. The results of this study suggest that older patient age, lower baseline BMD, and more pre-existing vertebral fractures were found to be risk factors for multiple vertebral compression fractures.

KW - Adjacent fracture

KW - Bone mineral density

KW - Compression fracture

KW - Osteoporosis

KW - Vertebroplasty

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U2 - 10.1097/BRS.0b013e3181ac8f07

DO - 10.1097/BRS.0b013e3181ac8f07

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VL - 34

SP - 1917

EP - 1922

JO - Spine

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SN - 1528-1159

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