Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

Tian Jong Chang, Cai Mei Zheng, Mei Yi Wu, Tzu Ting Chen, Yun Chun Wu, Yi Lien Wu, Hsin Ting Lin, Jing Quan Zheng, Nain Feng Chu, Yu Me Lin, Sui Lung Su, Kuo Cheng Lu, Jin Shuen Chen, Fung Chang Sung, Chien Te Lee, Yu Yang, Shang Jyh Hwang, Ming Cheng Wang, Yung Ho Hsu, Hung Yi ChiouSenyeong Kao, Yuh Feng Lin

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

This study investigated the characteristics of patients with different chronic kidney disease (CKD) stages according to various body mass index (BMI) categories and determined the influence of BMI in renal function deterioration. We conducted a multicenter, longitudinal cohort study based on the Epidemiology and Risk Factors Surveillance of CKD project (2008-2013) and National Health Insurance Research Database (2001-2013). A total of 7357 patients with CKD aged 20-85 years from 14 hospitals were included in the study. A higher male sex, diabetes mellitus (DM) and hypertension were noted among overweight and obese CKD patients, while more cancer prevalence was noted among underweight CKD patients. Charlson comorbidity index was significantly higher and correlated with BMI among late CKD patients. Patients with BMI < 18.5 kg/m2 exhibited non-significantly higher events of eGFR decline events in both early and late CKD stages than other BMI groups. BMI alone is not a determinant of CKD progression among our Taiwanese CKD patients. Obesity should be re-defined and body weight manipulation should be individualized in CKD patients. 
原文英語
文章編號6908
頁(從 - 到)6908
期刊Scientific Reports
8
發行號1
DOIs
出版狀態已發佈 - 十二月 1 2018

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ASJC Scopus subject areas

  • General

引用此

Chang, T. J., Zheng, C. M., Wu, M. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H., ... Lin, Y. F. (2018). Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population. Scientific Reports, 8(1), 6908. [6908]. https://doi.org/10.1038/s41598-018-24757-6