Recurrent minimal change disease post-allograft renal transplant

C. I. Jan, A. Chen, G. H. Sun, D. S. Yu, C. Y. Yen, J. S. Chen, Y. F. Lin

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

A young adult was diagnosed with steroid-resistant minimal change disease (MCD) without evidence of focal segmental glomerulosclerosis (FSGS) despite serial and detailed sectioning and screening of the renal biopsy. He received initial treatment with steroids and then cyclosporine plus low-dose steroids for 2 years. Renal function progressively deteriorated due to resistance to steroid and cyclosporine. Two months after initiation of hemodialysis, the patient received a living-related allogenic kidney transplant. However, recurrent nephrotic syndrome and renal insufficiency occurred after transplantation. In spite of aggressive treatment, renal function showed no significant improvement. The kidney graft was removed 2 weeks after transplantation. Serial sectioning and thorough sampling and screening revealed no evidence of FSGS, but light microscopy and electron microscopy showed the typical morphologic pattern of MCD, corresponding to the pretransplant diagnosis. We believe that this is the first reported case of recurrent MCD after renal transplant.

原文英語
頁(從 - 到)2888-2890
頁數3
期刊Transplantation Proceedings
35
發行號8
DOIs
出版狀態已發佈 - 十二月 2003
對外發佈Yes

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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