Recent advances in nanoparticle-based förster resonance energy transfer for biosensing, molecular imaging and drug release profiling

Nai Tzu Chen, Shih Hsun Cheng, Ching Ping Liu, Jeffrey S. Souris, Chen Tu Chen, Chung Yuan Mou, Leu Wei Lo

研究成果: 雜誌貢獻回顧型文獻同行評審

103 引文 斯高帕斯(Scopus)

摘要

Förster resonance energy transfer (FRET) may be regarded as a 'smart' technology in the design of fluorescence probes for biological sensing and imaging. Recently, a variety of nanoparticles that include quantum dots, gold nanoparticles, polymer, mesoporous silica nanoparticles and upconversion nanoparticles have been employed to modulate FRET. Researchers have developed a number of 'visible' and 'activatable' FRET probes sensitive to specific changes in the biological environment that are especially attractive from the biomedical point of view. This article reviews recent progress in bringing these nanoparticle-modulated energy transfer schemes to fruition for applications in biosensing, molecular imaging and drug delivery.

原文英語
頁(從 - 到)16598-16623
頁數26
期刊International journal of molecular sciences
13
發行號12
DOIs
出版狀態已發佈 - 12月 2012
對外發佈

ASJC Scopus subject areas

  • 催化
  • 分子生物學
  • 光譜
  • 電腦科學應用
  • 物理與理論化學
  • 有機化學
  • 無機化學

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