Quantitative determination of hydrazines derived from isoniazid in patients. I

Atsuko Noda, Tsuyoshi Goromaru, Kuang yang Hsu, Sadao Iguchi

研究成果: 雜誌貢獻文章

35 引文 斯高帕斯(Scopus)

摘要

Hydrazine formation took place in man after the oral administration of isoniazid. The successive excretion of free hydrazine, one of the well-known mutagens, was observed in the urine of the patients on INH-treatment. The intact INH and the other metabolites, acetyl-INH, acetyl-hydrazine and diacetylhydrazine, were also analyzed by gas chromatography-mass spectrometry.

原文英語
頁(從 - 到)132-141
頁數10
期刊Journal of Pharmacobio-Dynamics
1
發行號2
DOIs
出版狀態已發佈 - 1978
對外發佈Yes

ASJC Scopus subject areas

  • Pharmacology

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