Quality of life in adults with congenital heart disease: Biopsychosocial determinants and sex-related differences

Chun An Chen, Shih Cheng Liao, Jou Kou Wang, Chung I. Chang, Ing Sh Chiu, Yih Sharng Chen, Chun Wei Lu, Ming Tai Lin, Hsin Hui Chiu, Shuenn Nan Chiu, Yu Chuan Hua, Hung Chi Lue, Mei Hwan Wu

研究成果: 雜誌貢獻文章同行評審

36 引文 斯高帕斯(Scopus)

摘要

Objectives: To assess the quality of life (QoL) in adults with congenital heart disease (ACHD) and to explore the sex-related differences and biopsychosocial determinants in an Asian cohort. Design: Prospective cross-sectional clinical study. Setting: One tertiary medical centre in Taiwan. Patients and methods: The QoL of ACHD (≥20 years) was investigated using the Taiwanese version of the QoL questionnaire designed by the WHO, which assesses four domains of QoL (physical, psychological, social and environmental). Personality, psychological distress and family support were assessed using the Maudsley Personality Inventory, Brief Symptom Rating Scale, and the Family APGAR score, respectively. Results: A total of 289 patients (age 33.2±10.6 years; 36% men) were studied. ACHD women had significantly lower QoL scores in the physical and psychological domains compared to the age-matched general population, whereas no differences were observed between ACHD men and the general population. Multivariate analysis showed that female gender was associated with poorer physical QoL; the sex difference in the psychological QoL was mediated by psychological distress. Interaction analysis showed that the effect of family support on the psychological domain of QoL may be different by sex. The determinants of QoL varied between different domains. Extroversion personality trait, psychological distress and family support were common determinants of most domains of QoL. Conclusions: In ACHD, female gender was associated with poor physical and psychological QoL. The common denominators for QoL were primarily personality trait, psychological distress and family support, but not disease severity.

原文英語
頁(從 - 到)38-43
頁數6
期刊Heart
97
發行號1
DOIs
出版狀態已發佈 - 一月 2011
對外發佈

ASJC Scopus subject areas

  • 心臟病學與心血管醫學

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