Purpuric halo around hemangioma as a clue for primary systemic amyloidosis: Case report and review of literature

Yin Shuo Chang, Kuo Hsien Wang, Hsiou Hsin Tsai, Chung Hong Hu, Jan Show Chu

研究成果: 雜誌貢獻文章同行評審

摘要

Mucocutaneous lesion appears in up to 40% of patients with primary systemic amyloidosis (AL amyloidosis). The cutaneous signs may be co-expressed with other organ involvement or even solely presented as the first clue. We reported a case of systemic AL amyloidosis who was initially presented as a solitary hemangioma with a purpuric halo. Excisional biopsy revealed a hemangioma with amyloid deposited in thickened vascular walls. Systemic AL amyloidosis was diagnosed after thorough survey. The stage of disease at the time of initial treatment is the greatest prognostic factor. To our knowledge, this is the first case of systemic AL amyloidosis initially presented as a purpuric halo around hemangioma in Taiwan. This target-like lesion should be linked to systemic AL amyloidosis and early diagnosis is extraordinary important.
原文英語
頁(從 - 到)42-45
期刊Dermatologica Sinica
36
發行號1
DOIs
出版狀態已發佈 - 三月 2018

ASJC Scopus subject areas

  • Dermatology

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