Pulmonary rehabilitation improves exercise capacity and quality of life in underweight patients with chronic obstructive pulmonary disease

Chou Chin Lan, Mei Chen Yang, Chih Hsin Lee, Yi Chih Huang, Chun Yao Huang, Kuo Liang Huang, Yao Kuang Wu

研究成果: 雜誌貢獻文章

20 引文 (Scopus)

摘要

Background and objective: An estimated 20-40% of COPD patients are underweight. We sought to confirm the physiological and psychosocial benefits of pulmonary rehabilitation programmes (PRP) in underweight compared with non-underweight patients with COPD. Methods: Twenty-two underweight COPD patients with BMI 2, and 22 non-underweight COPD patients, who were matched for FEV 1 and age, were studied. All patients had moderate-to-very severe COPD. All patients participated in 12-week, hospital-based outpatient PRP consisting of two sessions per week. Baseline and post-PRP status were evaluated by spirometry, cardiopulmonary exercise testing, ventilatory muscle strength and the St. George's Respiratory Questionnaire (SGRQ). Results: At baseline, the age distribution and airflow obstruction were similar in underweight and non-underweight patients with COPD. Baseline exercise capacity, inspiratory muscle strength and SGRQ total and symptoms scores were significantly lower in the underweight patients (all P <0.05). After the PRP, there was significant weight gain in the underweight COPD patients (mean increase 0.8 kg, P = 0.01). There were also significant improvements in peak oxygen uptake, peak workload and the SGRQ total, symptoms, activity and impact scores in both underweight and non-underweight patients with COPD (all P <0.05). Conclusions: Underweight patients with COPD have impaired exercise capacity and health-related quality of life (HRQL). Exercise training with supplemental oxygen may result in significant weight gains and improvements in exercise capacity and HRQL. Exercise training is indicated for underweight patients with COPD. This study confirmed that impairment of exercise capacity and health-related quality of life was greater in underweight compared with non-underweight COPD patients. Exercise training resulted in significant weight gains, and improvements in exercise capacity and health-related quality of life. Exercise training is indicated for underweight patients with COPD.

原文英語
頁(從 - 到)276-283
頁數8
期刊Respirology
16
發行號2
DOIs
出版狀態已發佈 - 二月 2011
對外發佈Yes

指紋

Exercise Therapy
Thinness
Chronic Obstructive Pulmonary Disease
Quality of Life
Lung
Exercise
Rehabilitation
Weight Gain
Muscle Strength
Inspiratory Capacity
Oxygen
Respiratory Muscles
Spirometry
Age Distribution
Workload

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

引用此文

Pulmonary rehabilitation improves exercise capacity and quality of life in underweight patients with chronic obstructive pulmonary disease. / Lan, Chou Chin; Yang, Mei Chen; Lee, Chih Hsin; Huang, Yi Chih; Huang, Chun Yao; Huang, Kuo Liang; Wu, Yao Kuang.

於: Respirology, 卷 16, 編號 2, 02.2011, p. 276-283.

研究成果: 雜誌貢獻文章

Lan, Chou Chin ; Yang, Mei Chen ; Lee, Chih Hsin ; Huang, Yi Chih ; Huang, Chun Yao ; Huang, Kuo Liang ; Wu, Yao Kuang. / Pulmonary rehabilitation improves exercise capacity and quality of life in underweight patients with chronic obstructive pulmonary disease. 於: Respirology. 2011 ; 卷 16, 編號 2. 頁 276-283.
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abstract = "Background and objective: An estimated 20-40{\%} of COPD patients are underweight. We sought to confirm the physiological and psychosocial benefits of pulmonary rehabilitation programmes (PRP) in underweight compared with non-underweight patients with COPD. Methods: Twenty-two underweight COPD patients with BMI 2, and 22 non-underweight COPD patients, who were matched for FEV 1 and age, were studied. All patients had moderate-to-very severe COPD. All patients participated in 12-week, hospital-based outpatient PRP consisting of two sessions per week. Baseline and post-PRP status were evaluated by spirometry, cardiopulmonary exercise testing, ventilatory muscle strength and the St. George's Respiratory Questionnaire (SGRQ). Results: At baseline, the age distribution and airflow obstruction were similar in underweight and non-underweight patients with COPD. Baseline exercise capacity, inspiratory muscle strength and SGRQ total and symptoms scores were significantly lower in the underweight patients (all P <0.05). After the PRP, there was significant weight gain in the underweight COPD patients (mean increase 0.8 kg, P = 0.01). There were also significant improvements in peak oxygen uptake, peak workload and the SGRQ total, symptoms, activity and impact scores in both underweight and non-underweight patients with COPD (all P <0.05). Conclusions: Underweight patients with COPD have impaired exercise capacity and health-related quality of life (HRQL). Exercise training with supplemental oxygen may result in significant weight gains and improvements in exercise capacity and HRQL. Exercise training is indicated for underweight patients with COPD. This study confirmed that impairment of exercise capacity and health-related quality of life was greater in underweight compared with non-underweight COPD patients. Exercise training resulted in significant weight gains, and improvements in exercise capacity and health-related quality of life. Exercise training is indicated for underweight patients with COPD.",
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AU - Huang, Kuo Liang

AU - Wu, Yao Kuang

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AB - Background and objective: An estimated 20-40% of COPD patients are underweight. We sought to confirm the physiological and psychosocial benefits of pulmonary rehabilitation programmes (PRP) in underweight compared with non-underweight patients with COPD. Methods: Twenty-two underweight COPD patients with BMI 2, and 22 non-underweight COPD patients, who were matched for FEV 1 and age, were studied. All patients had moderate-to-very severe COPD. All patients participated in 12-week, hospital-based outpatient PRP consisting of two sessions per week. Baseline and post-PRP status were evaluated by spirometry, cardiopulmonary exercise testing, ventilatory muscle strength and the St. George's Respiratory Questionnaire (SGRQ). Results: At baseline, the age distribution and airflow obstruction were similar in underweight and non-underweight patients with COPD. Baseline exercise capacity, inspiratory muscle strength and SGRQ total and symptoms scores were significantly lower in the underweight patients (all P <0.05). After the PRP, there was significant weight gain in the underweight COPD patients (mean increase 0.8 kg, P = 0.01). There were also significant improvements in peak oxygen uptake, peak workload and the SGRQ total, symptoms, activity and impact scores in both underweight and non-underweight patients with COPD (all P <0.05). Conclusions: Underweight patients with COPD have impaired exercise capacity and health-related quality of life (HRQL). Exercise training with supplemental oxygen may result in significant weight gains and improvements in exercise capacity and HRQL. Exercise training is indicated for underweight patients with COPD. This study confirmed that impairment of exercise capacity and health-related quality of life was greater in underweight compared with non-underweight COPD patients. Exercise training resulted in significant weight gains, and improvements in exercise capacity and health-related quality of life. Exercise training is indicated for underweight patients with COPD.

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KW - quality of life

KW - underweight

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