摘要

Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95% CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95% CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.
原文英語
頁(從 - 到)523-532
期刊Environmental Pollution
232
DOIs
出版狀態已發佈 - 一月 2018

指紋

Welding
Fumes
Particulate Matter
Shipyards
Sleep
Metals
Lung
Cortisol
Serotonin
Hydrocortisone
Polysomnography
Biomarkers
Heavy Metals
Workplace
Heavy metals
Association reactions
Equipment and Supplies
Monitoring

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

引用此文

Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders. / Chuang, Hsiao Chi; Su, Ting Yao; Chuang, Kai Jen; Hsiao, Ta Chih; Lin, Hong Ling; Hsu, Yuan Ting; Pan, Chih Hong; Lee, Kang Yun; Ho, Shu Chuan; Lai, Ching Huang.

於: Environmental Pollution, 卷 232, 01.2018, p. 523-532.

研究成果: 雜誌貢獻文章

Chuang, Hsiao Chi ; Su, Ting Yao ; Chuang, Kai Jen ; Hsiao, Ta Chih ; Lin, Hong Ling ; Hsu, Yuan Ting ; Pan, Chih Hong ; Lee, Kang Yun ; Ho, Shu Chuan ; Lai, Ching Huang. / Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders. 於: Environmental Pollution. 2018 ; 卷 232. 頁 523-532.
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abstract = "Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 ± 94.1 μg/m3 PM2.5 and welding workers were exposed to 2166.5 ± 3149.1 μg/m3. Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 μg/m3 PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95{\%} CI = -0.007-0.000, p < 0.05) in all workers and with a decrease of 0.001 ng/mL in serotonin (95{\%} CI = -0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers.",
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AU - Chuang, Hsiao Chi

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AU - Chuang, Kai Jen

AU - Hsiao, Ta Chih

AU - Lin, Hong Ling

AU - Hsu, Yuan Ting

AU - Pan, Chih Hong

AU - Lee, Kang Yun

AU - Ho, Shu Chuan

AU - Lai, Ching Huang

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