This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analysis and the decrease of action induced by diazoxide. This view is not mentioned before and is the first one reporting this result.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Environmental Science(all)
Lee, L. M., Lu, C. C., Chung, H. H., & Cheng, J. T. (2012). Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats. Scientific World Journal, 2012, . https://doi.org/10.1100/2012/941685