Proliferating cell nuclear antigen (PCNA) immunolabeling as a prognostic factor in invasive ductal carcinoma of the breast in Taiwan

Jan Show Chu, Chiun Sheng Huang, King Jen Chang

研究成果: 雜誌貢獻文章

17 引文 斯高帕斯(Scopus)

摘要

To evaluate the prognostic significance of proliferating cell nuclear antigen (PCNA) in breast cancer, an immunohistochemical assay was performed in 150 patients with invasive ductal carcinomas. The PCNA labeling index (PCNA-LI) was classified into two subgroups at a cut-off point of 45% that gave the best prognostic estimates for PCNA in survival analyses. Seventy-eight tumors had a low PCNA-LI of ≤45% and 72 tumors had a high PCNA-LI of >45%. A high PCNA-LI correlated significantly with p53 overexpression (P

原文英語
頁(從 - 到)145-152
頁數8
期刊Cancer Letters
131
發行號2
DOIs
出版狀態已發佈 - 九月 25 1998
對外發佈Yes

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Biology
  • Oncology

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