Prognostic indicators for renal cell carcinoma: A multivariate analysis of 643 patients using the revised 1997 TNM staging criteria

Ke Hung Tsui, Oleg Shvarts, Robert B. Smith, Robert A. Figlin, Jean B. Dekernion, Arie Belldegrun

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372 引文 斯高帕斯(Scopus)

摘要

Purpose: We determine independent prognostic indicators for renal cell carcinoma using the revised 1997 TNM staging criteria. Materials and Methods: The records of 643 consecutive patients undergoing partial or radical nephrectomy at our institution between 1987 and 1998 were reviewed. Preoperative evaluation of functional status using the Eastern Cooperative Oncology Group (ECOG) criteria was performed in all cases. Renal cell carcinoma grade and stage were evaluated using the 1997 American Joint Committee on Cancer grading and TNM staging criteria, respectively. Patients were followed for a mean plus or minus standard deviation of 47 ± 40 months (median 87). Kaplan-Meier survival curves were used to determine 5-year cancer specific survival for all patient groups. Univariate analysis using log rank sum tests was performed to evaluate the prognostic significance of overall TNM stage, tumor stage, disease grade and ECOG status. Multivariate analysis was performed to determine which factors had an independent impact on survival of patients with renal cell carcinoma. Results: The 5-year cancer specific survival rate was 91%, 74%, 67% and 32% for TNM stages I, II, III and IV lesions, respectively (p
原文英語
頁(從 - 到)1090-1095
頁數6
期刊Journal of Urology
163
發行號4
DOIs
出版狀態已發佈 - 4月 2000
對外發佈

ASJC Scopus subject areas

  • 泌尿科學

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