Processing and properties of hydrophilic electrospun polylactic acid/beta-tricalcium phosphate membrane for dental applications

Hsin Tai Hu, Sheng Yang Lee, Chien Chung Chen, Yen Cheng Yang, Jen Chang Yang

研究成果: 雜誌貢獻文章同行評審

14 引文 斯高帕斯(Scopus)

摘要

Typical electrospun polylactic acid (PLA) membranes revealing potential hydrophobicity and inflammation from acid release during degradation are major drawbacks as an ideal guided tissue regeneration (GTR) barrier. This study investigated the in vitro degradation properties of electrospun PLA/beta-tricalcium phosphate (β-TCP) membranes treated by polyethylene oxide dip-coating process. After surface modification, the membranes revealed good wettability in contact angle measurement. The addition of β-TCP can render good pH buffering properties for electrospun PLA membranes during the in vitro degradation test. The mechanical properties of the hybrid membrane showed no significant difference in suture pullout force at a dried or wetted state. For cell adhesion and proliferation, the membranes with hydrophilicity can enhance the cell attachment at early stage. Overall, these results show that electrospinning combined with dip coating is a feasible processing technology for producing hydrophilic fibrous GTR membranes.
原文英語
頁(從 - 到)833-842
頁數10
期刊Polymer Engineering and Science
53
發行號4
DOIs
出版狀態已發佈 - 四月 2013

ASJC Scopus subject areas

  • 聚合物和塑料
  • 材料化學
  • 化學 (全部)

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