Primary peritoneal carcinosarcoma: A report of two cases

Hao Sheng Fu, Yen Chen Wu, Ching Hui Chen, Wei Min Liu, Chien Jui Cheng, Ching Wen Chang, I. De Wang, Yen Hsieh Chiu

研究成果: 雜誌貢獻文章

1 引文 (Scopus)

摘要

Objective: Carcinosarcomas also known as malignant mixed mullerian tumors (MMMTs) contain both carcinomatous and sarcomatous elements. Most MMMTs are arising from female genital tract, including ovaries, uterus and fallopian tubes. Extragenital carcinosarcomas are extremely rare, with an estimation less than 40 cases so far. Case report: We report two cases of primary peritoneal carcinosarcomas. An 81-year-old woman with pelvic peritoneal carcinosarcoma, heterologous type, was treated with incomplete surgery without further chemotherapy, and died of disease soon. The other one was a 76 year-old woman with abdominal peritoneal carcinosarcoma, homologous type. After optimal debulking surgery and subsequent 6 cycles of combination of paclitaxel and carboplatin chemotherapy, the patient is free of tumor half of year. Conclusion: Active therapy, including complete cytoreduction surgery and carboplatin-paclitaxel chemotherapy might offer a chance of disease control for these unusual primary peritoneal carcinosarcomas.

指紋

Carcinosarcoma
Malignant Mixed Tumor
Carboplatin
Paclitaxel
Drug Therapy
Fallopian Tubes
Uterus
Ovary
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

引用此文

@article{3a213bc6463b4f27ad11667c70629f24,
title = "Primary peritoneal carcinosarcoma: A report of two cases",
abstract = "Objective: Carcinosarcomas also known as malignant mixed mullerian tumors (MMMTs) contain both carcinomatous and sarcomatous elements. Most MMMTs are arising from female genital tract, including ovaries, uterus and fallopian tubes. Extragenital carcinosarcomas are extremely rare, with an estimation less than 40 cases so far. Case report: We report two cases of primary peritoneal carcinosarcomas. An 81-year-old woman with pelvic peritoneal carcinosarcoma, heterologous type, was treated with incomplete surgery without further chemotherapy, and died of disease soon. The other one was a 76 year-old woman with abdominal peritoneal carcinosarcoma, homologous type. After optimal debulking surgery and subsequent 6 cycles of combination of paclitaxel and carboplatin chemotherapy, the patient is free of tumor half of year. Conclusion: Active therapy, including complete cytoreduction surgery and carboplatin-paclitaxel chemotherapy might offer a chance of disease control for these unusual primary peritoneal carcinosarcomas.",
keywords = "Carcinosarcoma, Case report, Malignant mixed mullerian tumor, Primary peritoneal carcinosarcoma",
author = "Fu, {Hao Sheng} and Wu, {Yen Chen} and Chen, {Ching Hui} and Liu, {Wei Min} and Cheng, {Chien Jui} and Chang, {Ching Wen} and Wang, {I. De} and Chiu, {Yen Hsieh}",
year = "2019",
doi = "10.1016/j.tjog.2018.12.001",
language = "English",
journal = "Taiwanese Journal of Obstetrics and Gynecology",
issn = "1028-4559",
publisher = "臺灣婦產科醫學會",

}

TY - JOUR

T1 - Primary peritoneal carcinosarcoma

T2 - A report of two cases

AU - Fu, Hao Sheng

AU - Wu, Yen Chen

AU - Chen, Ching Hui

AU - Liu, Wei Min

AU - Cheng, Chien Jui

AU - Chang, Ching Wen

AU - Wang, I. De

AU - Chiu, Yen Hsieh

PY - 2019

Y1 - 2019

N2 - Objective: Carcinosarcomas also known as malignant mixed mullerian tumors (MMMTs) contain both carcinomatous and sarcomatous elements. Most MMMTs are arising from female genital tract, including ovaries, uterus and fallopian tubes. Extragenital carcinosarcomas are extremely rare, with an estimation less than 40 cases so far. Case report: We report two cases of primary peritoneal carcinosarcomas. An 81-year-old woman with pelvic peritoneal carcinosarcoma, heterologous type, was treated with incomplete surgery without further chemotherapy, and died of disease soon. The other one was a 76 year-old woman with abdominal peritoneal carcinosarcoma, homologous type. After optimal debulking surgery and subsequent 6 cycles of combination of paclitaxel and carboplatin chemotherapy, the patient is free of tumor half of year. Conclusion: Active therapy, including complete cytoreduction surgery and carboplatin-paclitaxel chemotherapy might offer a chance of disease control for these unusual primary peritoneal carcinosarcomas.

AB - Objective: Carcinosarcomas also known as malignant mixed mullerian tumors (MMMTs) contain both carcinomatous and sarcomatous elements. Most MMMTs are arising from female genital tract, including ovaries, uterus and fallopian tubes. Extragenital carcinosarcomas are extremely rare, with an estimation less than 40 cases so far. Case report: We report two cases of primary peritoneal carcinosarcomas. An 81-year-old woman with pelvic peritoneal carcinosarcoma, heterologous type, was treated with incomplete surgery without further chemotherapy, and died of disease soon. The other one was a 76 year-old woman with abdominal peritoneal carcinosarcoma, homologous type. After optimal debulking surgery and subsequent 6 cycles of combination of paclitaxel and carboplatin chemotherapy, the patient is free of tumor half of year. Conclusion: Active therapy, including complete cytoreduction surgery and carboplatin-paclitaxel chemotherapy might offer a chance of disease control for these unusual primary peritoneal carcinosarcomas.

KW - Carcinosarcoma

KW - Case report

KW - Malignant mixed mullerian tumor

KW - Primary peritoneal carcinosarcoma

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U2 - 10.1016/j.tjog.2018.12.001

DO - 10.1016/j.tjog.2018.12.001

M3 - Article

AN - SCOPUS:85059133333

JO - Taiwanese Journal of Obstetrics and Gynecology

JF - Taiwanese Journal of Obstetrics and Gynecology

SN - 1028-4559

ER -