Primary Cutaneous Anaplastic Large Cell Lymphoma With Positive ALK Expression and a Rapidly Progressive Cutaneous Nodule

Dan Xue, Xiuzhen Li, Yunqing Ren, Qi Liu, Yun Yen, Lijun Xue

研究成果: 雜誌貢獻文章同行評審

6 引文 斯高帕斯(Scopus)

摘要

Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a distinct entity from systemic ALCL (sALCL). sALCL usually shows immunohistochemical positivity for anaplastic lymphoma kinase (ALK) and epithelial membrane antigen (EMA), whereas these tests are negative in pcALCL. In contrast to sALCL, pcALCL is rarely found in children and young adults. We present here a case of a rare clinical condition in a 21-year-old woman, who has pcALCL with positive ALK and patchy EMA expression. She experiences a large, rapidly growing nodule without any outside-nodule manifestation. In conclusion, both ALK and EMA expression alone cannot distinguish pcALCL from secondary skin involvement by a sALCL.
原文英語
頁(從 - 到)333-335
頁數3
期刊International Journal of Surgical Pathology
23
發行號4
DOIs
出版狀態已發佈 - 六月 3 2015
對外發佈

ASJC Scopus subject areas

  • 解剖學
  • 病理學與法醫學
  • 手術

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