Prevalence of von Willebrand disease in women with iron deficiency anaemia and menorrhagia in Taiwan

Yeu Chin Chen, T. Y. Chao, S. N. Cheng, S. H. Hu, J. Y. Liu

研究成果: 雜誌貢獻文章同行評審

14 引文 斯高帕斯(Scopus)

摘要

Iron deficiency anaemia (IDA) is a frequently encountered disease, which can be attributed to menorrhagia. Most female patients with von Willebrand disease (VWD) have menorrhagia. The aim of this study was to investigate the prevalence of VWD in women with both IDA and menorrhagia in Taiwan. From January to December 2005 and November 2006 to January 2007, 56 consecutive patients with both IDA and menorrhagia were enrolled in this study. Their median age was 41 years (range 18-53). IDA was diagnosed by anaemia plus either low ferritin or transferrin saturation. Menorrhagia was evaluated by patient's menses history. Both von Willebrand factor antigen (VWF:Ag) and ristocetin cofactor activity (VWF:RCo) were measured for each patient. Bleeding time (BT) and platelet function analyser (PFA)-100 assay were determined as ancillary tests. The VWD diagnosis was established if: (i) both VWF:Ag (

原文英語
頁(從 - 到)768-774
頁數7
期刊Haemophilia
14
發行號4
DOIs
出版狀態已發佈 - 七月 2008
對外發佈Yes

ASJC Scopus subject areas

  • Hematology

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