摘要
A novel chitosan-based nanoparticle carrier was prepared in this study. The chitosan derivative, N,O-carboxymethylchitosan (NOCC) was reacted with gallic acid (GA) using a non-toxic water-soluble carbodiimide to obtain the NOCC-GA conjugate, and the chemical structure of the conjugate was characterized with FT-IR and NMR spectra. The antioxidant activity of the NOCC-GA conjugate was examined by DPPH and ABTS+ radical scavenging activity. The radical/pH-responsive properties of the NOCC-GA conjugate and its iron(II) complex were examined by fluorescence spectral and light transmittance studies. The mean particle sizes of the NOCC-GA conjugate and its iron(II) complex nanoparticles were determined by a light scattering method. The NOCC-GA conjugate and its iron(II) complex nanoparticles might provide a novel way to deliver antioxidative protein or natural products in future.
原文 | 英語 |
---|---|
頁(從 - 到) | 794-802 |
頁數 | 9 |
期刊 | Carbohydrate Polymers |
卷 | 84 |
發行號 | 2 |
DOIs | |
出版狀態 | 已發佈 - 3月 1 2011 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 有機化學
- 聚合物和塑料
- 材料化學