Pregnancy following oocyte donation and tubal embryo transfer in patients with premature ovarian failure: report of two cases.

Y. S. Yang, J. L. Hwang, H. N. Ho, Y. S. Kuo, Y. R. Lien, T. Y. Lee

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3 引文 斯高帕斯(Scopus)

摘要

Two pregnancies in patients with premature ovarian failure utilizing donated oocytes, in-vitro fertilization (IVF) and tubal embryo transfer (TET), are reported. The recipients received cyclic hormone replacement therapy for six months to prepare the endometrium for implantation. An evaluation cycle was tested to document that the hormone milieu established by the hormone replacement protocol was similar to that of a natural ovulatory cycle. During the oocyte donation cycle, the recipient received incremental estrogen replacement treatment of flexible length during the follicular phase of the donor's stimulated cycle to synchronize the recipient's endometrium to the donor's embryo. Concurrently, the donor underwent controlled ovarian hyperstimulation and transvaginal ultrasound-guided oocyte retrieval. After fertilization of the donated oocytes with sperm from the recipient's husband and cleavage of the fertilized oocytes into the 2- to 4-cell stage, laparoscopic embryo transfer into the recipient's fallopian tube was performed. Case 1 received 4 embryos by the TET procedure. Pregnancy was confirmed by visualization of a gestational sac in the uterine cavity 3 weeks after TET, but miscarriage occurred at the tenth gestational week. In Case 2, the pregnancy was established after TET of 2 embryos. Estrogen and progesterone supplements were maintained until day 100 after TET. The patient delivered a healthy male baby, weighing 2,520 g at 38 weeks of gestation.
原文英語
頁(從 - 到)688-692
頁數5
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
90
發行號7
出版狀態已發佈 - 一月 1 1991
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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