Pregnancy following in vitro fertilization and embryo transfer by Microsurgical Epididymal Sperm Aspiration from a patient with Congenital Absence of the Vas Deferens: A case report

Chii Rucy Tzeng, Sen Yuan Hsiao, Li Wei Chien, Shu Ru Chang, Han-Sun Chiang, Chien Chih Wu, An Chiun Chen

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

Congenital absence of the vas deferens (CAVD) has been considered a virtually untreatable cause of male infertility. Men with this condition have been shown on testicular biospy to have adequate spermatogenesis, and are theoretically producing sperm capable of fertilizing an oocyte. Yet epididymal transit was thought to be essential for the maturation of spermatozoa and development of their fertilizing ability since the characteristics of sperm motility improve as the sperm passes through the cauda. However recent studies in man have shown that spermatozoa aspirated from the obstructed caput epididymis and ductuli efferentia are, in fact, capable of fertilization in vitro. Microsurgical epididymal sperm aspiration (MESA) from the proximal region (caput) of the epididymis, obtained 0.5 × 106 sperm per ml, following washing and direct swim-up. Twelve oocytes were inseminated and three embryos were generated for transfer. The patient conceived and deliveried a healthy female baby weighting 2838 gm, on March 3, 1994. This is the first documentation in Taiwan of live birth resulting from MESA from a patient with CAVD combined with in vitro fertilization and embryo transfer.
原文英語
頁(從 - 到)161-164
頁數4
期刊Chinese Medical Journal (Taipei)
57
發行號2
出版狀態已發佈 - 二月 1996

ASJC Scopus subject areas

  • Medicine(all)

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