Predictors of the development of post-snakebite compartment syndrome

Chih Po Hsu, Jung Fang Chuang, Yu Pao Hsu, Shang Yu Wang, Chih Yuan Fu, Kuo Ching Yuan, Chih Hao Chen, Shih Ching Kang, Chien Hung Liao

研究成果: 雜誌貢獻文章

10 引文 (Scopus)

摘要

Background: To identify the factors associated with the development of post-snakebite compartment syndrome (PSCS) in snakebite patients and to analyze the clinical prognosis of these patients. Methods: We retrospectively reviewed the medical records of patients who presented to our institution with snakebites from March 2009 to December 2012. The clinical data, hospital course and outcome were all recorded. Results: A total of 136 patients were included in the present study. Nine patients developed PSCS and underwent fasciotomy. Relative to the non-PSCS group, the PSCS group demonstrated a significant increase in the white blood cell count (WBC, p = 0.006), segment form (Seg, p ≤ 0.001), aspartate aminotransferase level (AST, p = 0.002) and alanine aminotransferase level (ALT, p = 0.008). Elevated WBC count and AST level were identified as independent risk factors for PSCS (p = 0.028 and 0.037, respectively) in a multivariate analysis. Conclusions: Snakebite patients have a high likelihood of developing locoregional complications such as PSCS. Symptomatic snakebite patients should be observed for at least 48 h, and increased WBC counts and AST levels are risk factors for PSCS.

原文英語
文章編號97
期刊Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
23
發行號1
DOIs
出版狀態已發佈 - 十一月 11 2015
對外發佈Yes

指紋

Snake Bites
Compartment Syndromes
Aspartate Aminotransferases
Alanine Transaminase
Leukocyte Count
Medical Records
Multivariate Analysis

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

引用此文

Predictors of the development of post-snakebite compartment syndrome. / Hsu, Chih Po; Chuang, Jung Fang; Hsu, Yu Pao; Wang, Shang Yu; Fu, Chih Yuan; Yuan, Kuo Ching; Chen, Chih Hao; Kang, Shih Ching; Liao, Chien Hung.

於: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 卷 23, 編號 1, 97, 11.11.2015.

研究成果: 雜誌貢獻文章

Hsu, Chih Po ; Chuang, Jung Fang ; Hsu, Yu Pao ; Wang, Shang Yu ; Fu, Chih Yuan ; Yuan, Kuo Ching ; Chen, Chih Hao ; Kang, Shih Ching ; Liao, Chien Hung. / Predictors of the development of post-snakebite compartment syndrome. 於: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2015 ; 卷 23, 編號 1.
@article{a2a55b9b1f2146599fbb7d0c8dc361f1,
title = "Predictors of the development of post-snakebite compartment syndrome",
abstract = "Background: To identify the factors associated with the development of post-snakebite compartment syndrome (PSCS) in snakebite patients and to analyze the clinical prognosis of these patients. Methods: We retrospectively reviewed the medical records of patients who presented to our institution with snakebites from March 2009 to December 2012. The clinical data, hospital course and outcome were all recorded. Results: A total of 136 patients were included in the present study. Nine patients developed PSCS and underwent fasciotomy. Relative to the non-PSCS group, the PSCS group demonstrated a significant increase in the white blood cell count (WBC, p = 0.006), segment form (Seg, p ≤ 0.001), aspartate aminotransferase level (AST, p = 0.002) and alanine aminotransferase level (ALT, p = 0.008). Elevated WBC count and AST level were identified as independent risk factors for PSCS (p = 0.028 and 0.037, respectively) in a multivariate analysis. Conclusions: Snakebite patients have a high likelihood of developing locoregional complications such as PSCS. Symptomatic snakebite patients should be observed for at least 48 h, and increased WBC counts and AST levels are risk factors for PSCS.",
author = "Hsu, {Chih Po} and Chuang, {Jung Fang} and Hsu, {Yu Pao} and Wang, {Shang Yu} and Fu, {Chih Yuan} and Yuan, {Kuo Ching} and Chen, {Chih Hao} and Kang, {Shih Ching} and Liao, {Chien Hung}",
year = "2015",
month = "11",
day = "11",
doi = "10.1186/s13049-015-0179-y",
language = "English",
volume = "23",
journal = "Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine",
issn = "1757-7241",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Predictors of the development of post-snakebite compartment syndrome

AU - Hsu, Chih Po

AU - Chuang, Jung Fang

AU - Hsu, Yu Pao

AU - Wang, Shang Yu

AU - Fu, Chih Yuan

AU - Yuan, Kuo Ching

AU - Chen, Chih Hao

AU - Kang, Shih Ching

AU - Liao, Chien Hung

PY - 2015/11/11

Y1 - 2015/11/11

N2 - Background: To identify the factors associated with the development of post-snakebite compartment syndrome (PSCS) in snakebite patients and to analyze the clinical prognosis of these patients. Methods: We retrospectively reviewed the medical records of patients who presented to our institution with snakebites from March 2009 to December 2012. The clinical data, hospital course and outcome were all recorded. Results: A total of 136 patients were included in the present study. Nine patients developed PSCS and underwent fasciotomy. Relative to the non-PSCS group, the PSCS group demonstrated a significant increase in the white blood cell count (WBC, p = 0.006), segment form (Seg, p ≤ 0.001), aspartate aminotransferase level (AST, p = 0.002) and alanine aminotransferase level (ALT, p = 0.008). Elevated WBC count and AST level were identified as independent risk factors for PSCS (p = 0.028 and 0.037, respectively) in a multivariate analysis. Conclusions: Snakebite patients have a high likelihood of developing locoregional complications such as PSCS. Symptomatic snakebite patients should be observed for at least 48 h, and increased WBC counts and AST levels are risk factors for PSCS.

AB - Background: To identify the factors associated with the development of post-snakebite compartment syndrome (PSCS) in snakebite patients and to analyze the clinical prognosis of these patients. Methods: We retrospectively reviewed the medical records of patients who presented to our institution with snakebites from March 2009 to December 2012. The clinical data, hospital course and outcome were all recorded. Results: A total of 136 patients were included in the present study. Nine patients developed PSCS and underwent fasciotomy. Relative to the non-PSCS group, the PSCS group demonstrated a significant increase in the white blood cell count (WBC, p = 0.006), segment form (Seg, p ≤ 0.001), aspartate aminotransferase level (AST, p = 0.002) and alanine aminotransferase level (ALT, p = 0.008). Elevated WBC count and AST level were identified as independent risk factors for PSCS (p = 0.028 and 0.037, respectively) in a multivariate analysis. Conclusions: Snakebite patients have a high likelihood of developing locoregional complications such as PSCS. Symptomatic snakebite patients should be observed for at least 48 h, and increased WBC counts and AST levels are risk factors for PSCS.

UR - http://www.scopus.com/inward/record.url?scp=84947862595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84947862595&partnerID=8YFLogxK

U2 - 10.1186/s13049-015-0179-y

DO - 10.1186/s13049-015-0179-y

M3 - Article

C2 - 26561300

AN - SCOPUS:84947862595

VL - 23

JO - Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

JF - Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

SN - 1757-7241

IS - 1

M1 - 97

ER -