Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer

Medicine & Life Sciences

• Bevacizumab 91%
• Colorectal Neoplasms 65%
• Genes 33%
• metallopeptidase-1 31%
• Protein Interaction Maps 20%
• Platelet-Derived Growth Factor 18%
• Proteins 15%
• Down-Regulation 11%
• Protein Databases 10%
• Breast Neoplasms 10%
• cdc Genes 10%
• Databases 9%
• Cyclin-Dependent Kinases 9%
• Toll-Like Receptor 4 9%
• Gene Ontology 9%
• Protein-Serine-Threonine Kinases 9%
• Survival 9%
• Phosphatidylinositol 3-Kinase 8%
• Urinary Bladder Neoplasms 7%
• Phosphates 7%
• MicroRNAs 6%
• Datasets 6%
• Software 6%
• Therapeutics 5%
• Gene Expression 4%
• Drug Therapy 4%
• Neoplasms 2%

Agriculture & Biology

• colorectal neoplasms 100%
• genes 28%
• protein-protein interactions 24%
• platelet-derived growth factor 19%
• therapeutics 17%
• breast neoplasms 17%
• metalloproteinases 16%
• urinary bladder neoplasms 11%
• Toll-like receptor 4 11%
• world wide web 11%
• cancer therapy 10%
• phosphatidylinositol 3-kinase 9%
• cyclin-dependent kinase 9%
• prognosis 9%
• gene ontology 8%
• microRNA 7%
• drug therapy 7%
• threonine 7%
• serine 6%
• cell cycle 6%
• phosphotransferases (kinases) 6%
• neoplasms 5%
• phosphates 5%
• gene expression 4%
• proteins 2%

Chemical Compounds

• Resistance 51%
• Cyclin Dependent Kinase Inhibitor 44%
• Phosphoinositide 37%
• MicroRNA 33%
• Threonine 30%
• Metabolic 22%
• Phosphate 17%
• Protein 11%
• Molecule 9%