Predication the suppressing human oral cancer cell line by curcumin through the research of fas receptor

Po Yuan Chen, Yu Chi Wu, Tzu-Hurng Cheng, Tzu Ching Shih, Cing Tsan Tsai, Chieh Hsi Wu, Tzu Yu Hua, Yen Yu Huang, Chia Hsing Cheng, Ming Jen Fan

研究成果: 書貢獻/報告類型會議貢獻

摘要

Curcumin is commonly applied as food coloring and seasoning but recent research show that curcumin is able to enhance the activation of Fas receptor to the cancer cell apoptosis through extrinsic pathway. Oral cancer results from the particular habit of chewing betel nuts that Taiwanese have. The additive in betel nuts (such as lime) is the main reason that increase the cancer rate of people chewing betel nuts and further increase the death rate gradually. The major treatments for oral cancer are still chemotherapy and surgery. This research expects to perform the computer simulation to calculate the activity of curcumin to oral cancer as medicine. The pharmaceutical activity are evaluate by the score from docking procedure perform by simulation program. We hope this experiment can be the evidence that curcumin can practically be used as medicine for oral cancer therapy in future.

原文英語
主出版物標題Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011
頁面209-212
頁數4
DOIs
出版狀態已發佈 - 2011
對外發佈
事件2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011 - Taichung, 臺灣
持續時間: 10月 24 201110月 26 2011

出版系列

名字Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011

其他

其他2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011
國家/地區臺灣
城市Taichung
期間10/24/1110/26/11

ASJC Scopus subject areas

  • 生物工程
  • 生物醫學工程

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