Precision science on incidence and progression of early-detected small breast invasive cancers by mammographic features

Rene Wei Jung Chang, Shu Lin Chuang, Chen Yang Hsu, Amy Ming Fang Yen, Wendy Yi Ying Wu, Sam Li Sheng Chen, Jean Ching Yuan Fann, Laszlo Tabar, Robert A. Smith, Stephen W. Duffy, Sherry Yueh Hsia Chiu, Hsiu Hsi Chen

研究成果: 雜誌貢獻文章同行評審

摘要

The aim was to evaluate how the inter-screening interval affected the performance of screening by mammographic appearances. This was a Swedish retrospective screening cohort study with information on screening history and mammography features in two periods (1977–1985 and 1996–2010). The pre-clinical incidence and the mean sojourn time (MST) for small breast cancer allowing for sensitivity by mammographic appearances were estimated. The percentage of interval cancer against background incidence (I/E ratio) was used to assess the performance of mammography screening by different inter-screening intervals. The sensitivity-adjusted MSTs (in years) were heterogeneous with mammographic features, being longer for powdery and crushed stone-like calcifications (4.26, (95% CI, 3.50–5.26)) and stellate masses (3.76, (95% CI, 3.15–4.53)) but shorter for circular masses (2.65, (95% CI, 2.06–3.55)) in 1996–2010. The similar trends, albeit longer MSTs, were also noted in 1977–1985. The I/E ratios for the stellate type were 23% and 32% for biennial and triennial screening, respectively. The corresponding figures were 32% and 43% for the circular type and 21% and 29% for powdery and crushed stone-like calcifications, respectively. Mammography-featured progressions of small invasive breast cancer provides a new insight into personalized quality assurance, surveillance, treatment and therapy of early-detected breast cancer.
原文英語
文章編號1855
頁(從 - 到)1-14
頁數14
期刊Cancers
12
發行號7
DOIs
出版狀態已發佈 - 七月 2020

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

指紋 深入研究「Precision science on incidence and progression of early-detected small breast invasive cancers by mammographic features」主題。共同形成了獨特的指紋。

引用此