摘要

Unlike other deep cancers, oral squamous cell carcinoma (OSCC), which occurs in the oral cavity, is more easily monitored, and specimens for diagnosis are easier to collect. However, identifying reliable and sensitive markers for the early diagnosis and markers for identification of the recurrence of OSCC remains a challenge. This article mainly focused on reviewing recently identified potential biomarkers for a cytologic diagnosis during OSCC development. In addition, markers used in modern diagnostic technologies, including a sensitive labeling method and a photodynamic approach for cytologic diagnosis, are also described. Cytologic examinations using sensitive and specific biomarkers can improve the accuracy of the diagnosis. Hence, they can lead to appropriate treatment without delay and to the reduced recurrence of OSCC.
原文英語
頁(從 - 到)60-69
頁數10
期刊Journal of Dental Sciences
5
發行號2
DOIs
出版狀態已發佈 - 六月 2010

指紋

Oral Diagnosis
Squamous Cell Carcinoma
Biomarkers
Recurrence
Mouth Neoplasms
Mouth
Early Diagnosis
Technology

ASJC Scopus subject areas

  • Dentistry(all)

引用此文

Potential biomarkers for the cytologic diagnosis of oral squamous cell carcinoma. / Yang, Wei Chung Vivian; Chung, Ho Ren; Wu, Jia Yo; Yi, Chen; Wang, Duen Jeng; Lee, Sheng Yang.

於: Journal of Dental Sciences, 卷 5, 編號 2, 06.2010, p. 60-69.

研究成果: 雜誌貢獻回顧型文獻

@article{4bfda2438eb74c38bc062c73783c7ca7,
title = "Potential biomarkers for the cytologic diagnosis of oral squamous cell carcinoma",
abstract = "Unlike other deep cancers, oral squamous cell carcinoma (OSCC), which occurs in the oral cavity, is more easily monitored, and specimens for diagnosis are easier to collect. However, identifying reliable and sensitive markers for the early diagnosis and markers for identification of the recurrence of OSCC remains a challenge. This article mainly focused on reviewing recently identified potential biomarkers for a cytologic diagnosis during OSCC development. In addition, markers used in modern diagnostic technologies, including a sensitive labeling method and a photodynamic approach for cytologic diagnosis, are also described. Cytologic examinations using sensitive and specific biomarkers can improve the accuracy of the diagnosis. Hence, they can lead to appropriate treatment without delay and to the reduced recurrence of OSCC.",
keywords = "Biomarkers, Cytologic diagnosis, Oral squamous cell carcinoma",
author = "Yang, {Wei Chung Vivian} and Chung, {Ho Ren} and Wu, {Jia Yo} and Chen Yi and Wang, {Duen Jeng} and Lee, {Sheng Yang}",
year = "2010",
month = "6",
doi = "10.1016/S1991-7902(10)60010-4",
language = "English",
volume = "5",
pages = "60--69",
journal = "Journal of Dental Sciences",
issn = "1991-7902",
publisher = "中華牙醫學會",
number = "2",

}

TY - JOUR

T1 - Potential biomarkers for the cytologic diagnosis of oral squamous cell carcinoma

AU - Yang, Wei Chung Vivian

AU - Chung, Ho Ren

AU - Wu, Jia Yo

AU - Yi, Chen

AU - Wang, Duen Jeng

AU - Lee, Sheng Yang

PY - 2010/6

Y1 - 2010/6

N2 - Unlike other deep cancers, oral squamous cell carcinoma (OSCC), which occurs in the oral cavity, is more easily monitored, and specimens for diagnosis are easier to collect. However, identifying reliable and sensitive markers for the early diagnosis and markers for identification of the recurrence of OSCC remains a challenge. This article mainly focused on reviewing recently identified potential biomarkers for a cytologic diagnosis during OSCC development. In addition, markers used in modern diagnostic technologies, including a sensitive labeling method and a photodynamic approach for cytologic diagnosis, are also described. Cytologic examinations using sensitive and specific biomarkers can improve the accuracy of the diagnosis. Hence, they can lead to appropriate treatment without delay and to the reduced recurrence of OSCC.

AB - Unlike other deep cancers, oral squamous cell carcinoma (OSCC), which occurs in the oral cavity, is more easily monitored, and specimens for diagnosis are easier to collect. However, identifying reliable and sensitive markers for the early diagnosis and markers for identification of the recurrence of OSCC remains a challenge. This article mainly focused on reviewing recently identified potential biomarkers for a cytologic diagnosis during OSCC development. In addition, markers used in modern diagnostic technologies, including a sensitive labeling method and a photodynamic approach for cytologic diagnosis, are also described. Cytologic examinations using sensitive and specific biomarkers can improve the accuracy of the diagnosis. Hence, they can lead to appropriate treatment without delay and to the reduced recurrence of OSCC.

KW - Biomarkers

KW - Cytologic diagnosis

KW - Oral squamous cell carcinoma

UR - http://www.scopus.com/inward/record.url?scp=78649234284&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649234284&partnerID=8YFLogxK

U2 - 10.1016/S1991-7902(10)60010-4

DO - 10.1016/S1991-7902(10)60010-4

M3 - Review article

VL - 5

SP - 60

EP - 69

JO - Journal of Dental Sciences

JF - Journal of Dental Sciences

SN - 1991-7902

IS - 2

ER -