Postoperative radiotherapy for primary early oral tongue cancer with pathologic N1 neck

Tseng Cheng Chen, Chi Te Wang, Jenq Yuh Ko, Pei Jen Lou, Tsung Lin Yang, Lai Lei Ting, Chun Wei Wang, Ya Ling Hu, Cheng Ping Wang

研究成果: 雜誌貢獻文章同行評審

23 引文 斯高帕斯(Scopus)

摘要

Background. The benefit of postoperative radiotherapy (PORT) for early squamous cell carcinoma of the tongue (SCCOT) with pathologic N1 disease remains unclear. Methods. The medical records of all patients with pathologic T1-2/N0-1 SCCOT who underwent wide excision of the primary tumor and neck dissection between 1980 and 2002 were reviewed. Results. There were 59 patients analyzed, including 28 patients with and 31 patients without PORT. The 5-year disease-free survival rates were 81.2% and 53% for the patients with and without PORT, respectively (p = .03). The overall 5-year survival rates were 77% and 70.5% for the patients with and without PORT, respectively (p = .36). Multivariate analyses showed that PORT had the only protective effect (p = .01) and extracapsular spread (ECS) was the only significantly adverse factor for locoregional recurrence (p = .03). Conclusions. Approximately one-third of the patients who received only surgery had locoregional recurrence. PORT significantly improved the disease-free survival.

原文英語
頁(從 - 到)555-561
頁數7
期刊Head and Neck
32
發行號5
DOIs
出版狀態已發佈 - 五月 1 2010

ASJC Scopus subject areas

  • Otorhinolaryngology

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